Manifestations neurologiques de la maladie de Behçet

Noël, Nicolas; Drier, Aurélie; Wechsler, B.; Piette, Jean Charles; Paz, Raquel de; Dormont, Didier; Cacoub, Patrice; Saadoun, David

doi:10.1016/j.revmed.2013.10.332

Cited by 25 publications

(12 citation statements)

References 52 publications

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“…At the cerebral level, non-parenchymal vascular central nervous system (CNS) involvements include cerebral venous sinus thrombosis (CVST), arterial occlusion, and/or aneurysms (72). CVST represents 10-30% of all neurological BS manifestations (73). The concomitant presence of both cerebral arterial manifestations and CVST is extremely rare (74).…”

Section: Extra-parenchymal Neurological and Peripheral Vascular Phenomentioning

confidence: 99%

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Treating the Different Phenotypes of Behçet's Syndrome

et al. 2019

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Behçet's syndrome (BS) is a multisystemic vasculitis, characterized by different clinical involvements, including mucocutaneous, ocular, vascular, neurological, and gastrointestinal manifestations. Based on this heterogeneity, BS can be hardly considered as a single clinical entity. Growing evidence supports that, within BS, different phenotypes, characterized by clusters of co-existing involvements, can be distinguished. Namely, three major BS phenotypes have been reported: (a) the mucocutaneous and articular phenotype, (b) the extra-parenchymal neurological and peripheral vascular phenotype, and (c) the parenchymal neurological and ocular phenotype. To date, guidelines for the management of BS have been focused on the pharmacological treatment of each specific BS manifestation. However, tailoring the treatments on patient's specific phenotype, rather than on single disease manifestation, could represent a valid strategy for a personalized therapeutic approach to BS. In the present literature review, we summarize current evidence on the pharmacological treatments for the first-, second-, and third-line treatment of the major BS phenotypes.

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Section: Extra-parenchymal Neurological and Peripheral Vascular Phenomentioning

confidence: 99%

“…The involvement of the parenchymal CNS is a major cause of morbidity and mortality in BS (73,85). In a study conducted on 200 neuro-BS out-patients, 162 had parenchymal CNS involvement (72).…”

Section: Parenchymal Cns and Ocular Phenotype Evidence On The Phenotypementioning

confidence: 99%

Treating the Different Phenotypes of Behçet's Syndrome

et al. 2019

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“…involvement, known as "Neuro-BS" (NBS) [1][2][3]. BS inflammatory features were studied in several genetics studies with focus on single nucleotide polymorphisms (SNPs) of genes involved in inflammation and immune response [4,5].…”

Section: Resultsmentioning

confidence: 99%

AB0013 GENOMIC PROFILING OF INFLAMMATION-RELATED GENES IN NEURO-BEHçET SYNDROME: A PRELIMINARY ITALIAN STUDY

Padula

Leccese²,

Lascaro³

et al. 2019

Abstracts Accepted for Publication

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“…Neurolgical manifestations of Behcet's are stroke, cranial nerve palsies, aseptic meningitis. Mortality in Neuro-Behcet's is as high as 10% (4) . Other rare manifestations include pulmonary arteritis, coronary arteritis, and endocarditis.…”

Section: Discussionmentioning

confidence: 99%

Unusual association of leptomeningitis, pachymeningitis, dural sinus thrombosis, posterior uveitis and pathergy in alady with Behcet’s disease

B¹

2018

jmscr

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Manifestations neurologiques de la maladie de Behçet

Cited by 25 publications

References 52 publications

Treating the Different Phenotypes of Behçet's Syndrome

Treating the Different Phenotypes of Behçet's Syndrome

AB0013 GENOMIC PROFILING OF INFLAMMATION-RELATED GENES IN NEURO-BEHçET SYNDROME: A PRELIMINARY ITALIAN STUDY

Unusual association of leptomeningitis, pachymeningitis, dural sinus thrombosis, posterior uveitis and pathergy in alady with Behcet’s disease

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