Plaque-Type Glomuvenous Malformations Successfully Treated Using Combined Pulsed Dye Laser and Neodymium-Doped Yttrium Aluminum Garnet Laser

Multiple Bluish Nodules in a 20-Year-Old Female with Similar Lesions in Her Father

“…Many case reports and studies demonstrated satisfying efficacy using laser treatments on GVM lesions. Dual-wavelength Pulsed Dye Laser and Neodynium-doped Yttrium Aluminium Garnet laser (PDL-Nd:YAG) showed the most promising results in 60% of size reduction and improvement in color with safety profile [20], the youngest patient successfully treated was reported of a 6-month-old girl, with less cutaneous adverse effects compared to Nd:YAG alone, the latter more frequently resulted in ulceration and scarring, especially in children [21].…”

Laser Therapy for an Acquired Glomuvenous Malformation (Glomus Tumour)

“…Glomuvenous malformations (GVMs) (previously known as glomus tumours) are uncommon, benign, vascular neoplasms typically arising in young adults as a solitary blue-red papule or nodule of the distal extremities. 1-3 Subungual sites are most commonly affected. Pain from GVMs is often induced from fluctuations in temperature or pressure.…”

“…Most GVMs occur sporadically and are solitary, 4 although multiple tumours can be familial secondary to loss of function mutations in the glomulin gene on chromosome 1p21. 2,5 Current treatments include surgical excision and sclerotherapy, often with high recurrence rates and poor cosmetic results. 3,6…”

Long‐Pulsed Neodymium‐Doped Yttrium Aluminum Garnet Laser for Glomuvenous Malformations in Adolescents

“…GVMs can be sporadic or familial and occur because of loss‐of‐function mutations in the GLMN gene . Treatment options include sclerotherapy and surgery; various laser modalities have also been described . Sclerotherapy may require multiple treatments, often necessitating anesthesia, and produces postoperative inflammation and discomfort.…”

“…Nd:YAG laser can be extremely effective in the treatment of venous malformations. Reports on laser modalities for GVMs exist but are rare in children and teens. We describe long‐pulsed Nd:YAG laser as monotherapy for GVMs in children and adolescents.…”