A Systematic Review of the Economic and Humanistic Burden of Illness in Irritable Bowel Syndrome and Chronic Constipation

Nellesen, Dave; Yee, K.; Chawla, Anita; Lewis, Barbara; Carson, Robyn

doi:10.18553/jmcp.2013.19.9.755

Cited by 195 publications

(173 citation statements)

References 46 publications

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“…Our findings are found to be similar among medical students and interns of King Abdulaziz University in Jeddah. Moreover, they are in agreement with Korean medical students [15] [3]. In contrast, Basandra et al (2014) found that there are significant associations between IBS and the consumption of fatty food among medical students from Northern India [22].…”

Section: Discussionsupporting

confidence: 68%

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Irritable Bowel Syndrome among Medical Students and Interns in King Faisal University

Alsuwailm¹,

AL-Qahtani²,

AL-Hulaibi³

et al. 2017

OJPM

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Background: One of the most highly prevalent costly gastrointestinal disorders is IBS. It is a consequence of emotional conflicts and stress. So people who are in medical education, they have highest percentage of IBS. Objective: To estimate the prevalence of IBS and its effects on the academic achievement among medical students of KFU, Al-Hasa, Saudi Arabia. Methods: A crosssectional study was carried out among medical students and interns from August 2015 to September 2016 at (KFU) in Al-Hasa, Saudi Arabia. All participants were asked to complete a confidential self-administered questionnaire. Diagnosis of IBS was according to Rome III criteria. Results: 173 medical students completed the survey. The prevalence of IBS was 44.5%, with a high prevalence in females (31.8%). IBS was present significantly higher among students who experience emotional stress in the past 6-month (25.4%) and higher among students with a positive family history of IBS. Moreover, IBS was associated with a decrease in the academic performance among medical students (p < 0.05). Conclusion: The study revealed a high percentage of IBS among medical students and interns in KFU. Female gender, having emotional stress in the past 6 months and family history of IBS were the main predictors of IBS. However, the main predictor of IBS was in family history.

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Section: Discussionsupporting

confidence: 68%

“…The burden of IBS is significant enough to contribute to a considerable impairment in quality of life by affecting the person's social and emotional functioning leading to depression, decrease academic achievement and increase rate of absences from schools and work stations [15].…”

Section: Introductionmentioning

confidence: 99%

Irritable Bowel Syndrome among Medical Students and Interns in King Faisal University

Alsuwailm¹,

AL-Qahtani²,

AL-Hulaibi³

et al. 2017

OJPM

View full text Add to dashboard Cite

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“…19,20 It affects daily life especially in those with abdominal symptoms 21 and resulted in 13.7 million days of restricted activity; missing work or school in 12% and impaired ability to work in 60% of patients. 20 In the United States, the direct expenditure per-patient for constipation which includes medications, hospitalizations, out-patient services, emergency visits, and laboratory tests ranged from $1912 to $7522 per year 19 and increased several-fold between 1997 and 2010. 22 Moreover, a study revealed that up to 50% of chronic constipation and IBS patients use alternative or non-prescription medications, especially by women and patients with higher education.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and Treatment of Dyssynergic Defecation

Rao

Patcharatrakul

2016

J Neurogastroenterol Motil

189

149

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Dyssynergic defecation is common and affects up to one half of patients with chronic constipation. This acquired behavioral problem is due to the inability to coordinate the abdominal and pelvic floor muscles to evacuate stools. A detailed history, prospective stool diaries, and a careful digital rectal examination will not only identify the nature of bowel dysfunction, but also raise the index of suspicion for this evacuation disorder. Anorectal physiology tests and balloon expulsion test are essential for a diagnosis. Newer techniques such as high-resolution manometry and magnetic resonance defecography can provide mechanistic insights. Recently, randomized controlled trials have shown that biofeedback therapy is more effective than laxatives and other modalities, both in the short term and long term, without side effects. Also, symptom improvements correlated with changes in underlying pathophysiology. Biofeedback therapy has been recommended as the first-line of treatment for dyssynergic defecation. Here, we provide an overview of the burden of illness and pathophysiology of dyssynergic defecation, and how to diagnose and treat this condition with biofeedback therapy.

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“…Reported rates of co-morbid anxiety and depression in IBS range between 30 to 60%, depending on type of health care setting and country of origin (Drossman et al, 1999;Kabra & Nadkarni, 2013). IBS has significant financial and humanistic burdens (Nellesen, Yee, Chawla, Lewis, & Carson, 2013;Spiller et al, 2007) and treatment relies on lifestyle advice, and medical and psychological therapies (Akehurst & Kaltenthaler, 2001;Talley, Holtmann, & Walker, 2015).…”

Section: Introductionmentioning

confidence: 99%

The role of high expectations of self and social desirability in emotional processing in individuals with irritable bowel syndrome: A qualitative study

Sibelli

Chalder

Everitt

et al. 2017

British J Health Psychol

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ObjectivesAlthough high levels of distress are associated with the onset and severity of IBS, it is unclear how this relates to emotional processing, particularly in relation to maintenance of symptoms and treatment outcome. This qualitative study embedded within a randomised controlled trial aimed to explore how individuals with refractory IBS experience, express and manage their emotions after either therapist-delivered Cognitive Behavioural Therapy (TCBT) or webbased CBT (WBCBT) compared to Treatment as Usual (TAU). DesignCross-sectional qualitative study. MethodsFifty two semi-structured interviews were conducted at post-treatment with 17 TCBT participants, 17 WBCBT and 18 TAU. The transcripts were analysed using inductive thematic analysis with grounded theory elements. NVivo 11 was used to compare themes across groups. ResultsAcross all groups, high expectations of self was a recurring reason for how participants experienced and expressed their emotions. Three themes with sub-themes captured how high expectations related to specific aspects of emotional processing: perceived causes of Running head: EMOTIONAL PROCESSING IN IBS 2 emotions, strategies for coping with emotions (bottling up, avoiding emotions and active coping strategies) and the perceived interplay between emotions and IBS symptoms. ConclusionsPatients recognised that their IBS symptoms both triggered and were triggered by negative emotions. However, there was a tendency to bottle up or avoid negative emotions for reasons of social desirability regardless of whether patients had CBT for IBS or not. Future psychological interventions in IBS may benefit from addressing negative beliefs about expressing emotions, promoting assertive emotional expression and encouraging the experience of positive emotions.

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A Systematic Review of the Economic and Humanistic Burden of Illness in Irritable Bowel Syndrome and Chronic Constipation

Cited by 195 publications

References 46 publications

Irritable Bowel Syndrome among Medical Students and Interns in King Faisal University

Irritable Bowel Syndrome among Medical Students and Interns in King Faisal University

Diagnosis and Treatment of Dyssynergic Defecation

The role of high expectations of self and social desirability in emotional processing in individuals with irritable bowel syndrome: A qualitative study

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