Carotid Intima-Media Thickness – A Potential Predictor for Rupture Risk of Intracranial Aneurysms

Lundervik, Marianne; Fromm, Annette; Haaland, Øystein Ariansen; Waje‐Andreassen, Ulrike; Svendsen, Frode; Thomassen, Lars; Helland, Christian A.

doi:10.1111/ijs.12159

Cited by 4 publications

(10 citation statements)

References 20 publications

(26 reference statements)

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“…CIMT values have been shown to be compatible with histological findings of atherosclerosis (26). Studies have described CIMT as a non-invasive, rapid, easily repeatable, economical and useful method of determining atherosclerosis in the early period (9,11,12,27,28).…”

Section: Discussionmentioning

confidence: 97%

“…Although the relation between CIMT and various atherosclerotic vascular diseases such as CAD, PAD and CVD has been clearly revealedthe findings of studies investigating CIMT in aneurysmal diseases are inconsistent (9)(10)(11)(12). One study reported that CIMT values in patients with AAA and PAD increased at a similar rate to those of healthy volunteers (29).…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have investigated the relation between increased CIMT and various vascular diseases, such as coronary artery disease (CAD), peripheral artery disease (PAD), intracranial arterial aneurysms, and abdominal aortic aneurysms (AAA) (9,10,11,12). However, the number of studies concerning aTAA is very small (13).…”

Section: Introductionmentioning

confidence: 99%

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The role of vascular elastography and carotid artery intima media thickness methods in the determination of non-syndromic ascending thoracic aortic aneurysm

Hemsinli¹,

Korkmaz²,

Baki³

et al. 2017

J Turgut Ozal Med Cent

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Aim:The role of atherosclerosis in the pathogenesis of ascending thoracic aortic aneurysms is still uncertain. Ultrasonic elastography is a new diagnostic method, the use of which has diversified considerably in recent years. An increase in intima media thickness in the carotid arteries is an early finding of atherosclerosis. Our purpose was to investigate the effect of atherosclerosis in the development of ascending thoracic aortic aneurysms and to be able to recommend a non-invasive and inexpensive scanning method aiming at early diagnosis. Material and Methods: Thirty-three patients with ascending thoracic aortic aneurysms (aTAA group) and 40 patients with normal measurement (control group) values were included in the study. The carotid artery intima media thicknessof carotid arteries were measured using B mode ultrasonography. Elastographic examination of the intima-media was then performed. Results: Body mass index, past smoking status, hypertension, presence of coronary artery disease and hyperlipidemia were higher in the aTAA group than in the control group (p<0.05). No significant difference was determined between these two groups' ultrasonic elastography or intima media thickness in the carotid arteries values (p<0.05). Conclusions: Our findings suggest that the effect of atherosclerosis in the pathogenesis of ascending thoracic aortic aneurysms is limited. Vascular ultrasonic elastography and intima media thickness determination in the carotid arteries appear not to be effective in the evaluation of ascending thoracic aortic aneurysms.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

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The role of vascular elastography and carotid artery intima media thickness methods in the determination of non-syndromic ascending thoracic aortic aneurysm

Hemsinli¹,

Korkmaz²,

Baki³

et al. 2017

J Turgut Ozal Med Cent

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“…Спільні чинники ризику як атеросклерозу, так і ЦА, включають АГ і тютюнопаління [2,9]. Хоча вся су-динна система піддається впливу цих чинників, ЦА та АБ виникають зазвичай у різних ділянках при локаль-них гемодинамічних змінах на тлі системної АГ [2,10].…”

Section: вступunclassified

“…Хоча вся су-динна система піддається впливу цих чинників, ЦА та АБ виникають зазвичай у різних ділянках при локаль-них гемодинамічних змінах на тлі системної АГ [2,10]. Є дані, що серед пацієнтів з атеросклерозом велика частота ЦА [9]. В іншому дослідженні нерозірвані ЦА були виявлені у 4,6% пацієнтів з інсультом, тоді як серед здорових осіб -у 3,9%.…”

Section: вступunclassified

Ultrasonic evaluation of hemodynamics and morphology of the major arteries of the neck in patients with essential hypertension associated with hemorrhagic stroke

Tkachyshyn

2018

Ukr Neurosurg J

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Inflammation As a Biomarker Method in Lifespan Developmental Methodology

Wilson¹,

Woody²,

Kiecolt‐Glaser³

2018

Oxford Research Encyclopedia of Psychology

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Inflammatory markers provide invaluable tools for studying health and disease across the lifespan. Inflammation is central to the immune system’s response to infection and wounding; it also can increase in response to psychosocial stress. In addition, depression and physical symptoms such as pain and poor sleep can promote inflammation and, because these factors fuel each other, all contribute synergistically to rising inflammation. With increasing age, persistent exposure to pathogens and stress can induce a chronic proinflammatory state, a process known as inflamm-aging. Inflammation’s relevance spans the life course, from childhood to adulthood to death. Infection-related inflammation and stress in childhood, and even maternal stress during pregnancy, may presage heightened inflammation and poor health in adulthood. In turn, chronically heightened inflammation in adulthood can foreshadow frailty, functional decline, and the onset of inflammatory diseases in older age. The most commonly measured inflammatory markers include C-reactive protein (CRP) and proinflammatory cytokines interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α). These biomarkers are typically measured in serum or plasma through blood draw, which capture current circulating levels of inflammation. Dried blood spots offer a newer, sometimes less expensive collection method but can capture only a limited subset of markers. Due to its notable confounds, salivary sampling cannot be recommended. Inflammatory markers can be added to a wide range of lifespan developmental designs. Incorporating even a single inflammatory assessment to an existing longitudinal study can allow researchers to examine how developmental profiles and inflammatory status are linked, but repeated assessments must be used to draw conclusions about the associations’ temporal order and developmental changes. Although the various inflammatory indices can fluctuate from day to day, ecological momentary assessment and longitudinal burst studies have not yet incorporated daily inflammation measurement; this represents a promising avenue for future research. In conclusion, mounting evidence suggests that inflammation affects health and disease across the lifespan and can help to capture how stress “gets under the skin.” Incorporating inflammatory biomarkers into developmental studies stands to enhance our understanding of both inflammation and lifespan development.

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Carotid Intima-Media Thickness – A Potential Predictor for Rupture Risk of Intracranial Aneurysms

Cited by 4 publications

References 20 publications

The role of vascular elastography and carotid artery intima media thickness methods in the determination of non-syndromic ascending thoracic aortic aneurysm

The role of vascular elastography and carotid artery intima media thickness methods in the determination of non-syndromic ascending thoracic aortic aneurysm

Ultrasonic evaluation of hemodynamics and morphology of the major arteries of the neck in patients with essential hypertension associated with hemorrhagic stroke

Inflammation As a Biomarker Method in Lifespan Developmental Methodology

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