Abstract:Many particulate materials of sizes approximating that of a cell disseminate after being introduced into the body. While some move about within phagocytic inflammatory cells, others appear to move about outside of, but in contact with, such cells. In this report, we provide unequivocal photomicroscopic evidence that cultured, mature, human dendritic cells can transportin extracellular fashion over significant distances both polymeric beads and tumor cells. At least in the case of polymeric beads, both fibrinog… Show more
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