241 Antidepressant Effect of Aqueous and Hydroalcoholic Extracts of Cinnamon zeylanicum in the Forced Swimming Test

A medicinal herb, Melissa officinalis L. ameliorates depressive-like behavior of rats in the forced swimming test via regulating the serotonergic neurotransmitter

“…Numerous bioactivities of MO, such as antioxidant (Mimica-Dukic et al, 2004), anti-cancer cell proliferation (Encalada et al, 2011), anti-obesity (Lee et al, 2008) and anti-anxiety (Kennedy et al, 2006) (Taiwo et al, 2012). Similarly, acute administration of the essential oil or aqueous extract of MO by the intraperitoneal route also decrease the immobility time of rats in the FST (Emamghoreishi and Talebianpour, 2009). Lopez et al showed that both the ethanol and water extracts of MO (WMO) could inhibit the activity of monoamine oxidase A (MAO A ), the major metabolic enzyme of monoaminergic neurotransmitters (Lopez et al, 2009).…”

Evaluation of the Antidepressant-like Activity of the Crude Extract and Solvent Fractions of Rosa Abyssinica Lindley (Rosaceae) Using Rodent Models of Depression

“…The activity of the extract in both models observed in the present study thus strengthens the possibility that Rosa abyssinica indeed is a potential candidate for the treatment of major depressive disorders. The variability in the response of different antidepressants in these models, however, indicates potentially different substrates and neurochemical pathways mediating performance in these tests [43,44]. These issues possibly underlie the observed behavioral differences between the two tests in the current study.…”

A Review Study on the Traditional Plants has Potential Antidepressant Property

“…The parts used are leaves, seeds and roots. It is used for fever, menstrual problems, tuberculosis and as a tonic for general weakness and illness [59]. Cassia occidentalis leaf extracts have antibacterial [60][61][62], antiplasmodial [63], antimutagenic [64], hepatoprotective [65] and anti-diabetic activity [66].…”