Association of cardiac events with coronary artery disease detected by 64-slice or greater coronary CT angiography: A systematic review and meta-analysis

Habib, Phillip; Green, Jacinta; Butterfield, Ryan; Kuntz, Gretchen; Murthy, Raguveer; Kraemer, Dale F.; Percy, Robert F.; Miller, Alan B.; Strom, Joel A.

doi:10.1016/j.ijcard.2013.08.096

Cited by 47 publications

(29 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A normal initial scan was associated with low prevalence of >50% stenosis at the repeat scan. In conjunction with previous literature showing that patients with nonobstructive lesion had higher event rates than those with normal CCTA, 22,23 our data may support that lesions with mild to moderate stenosis can become more important clinically.…”

Section: Discussionsupporting

confidence: 89%

Repeat Coronary Computed Tomographic Angiography in Patients With a Prior Scan Excluding Significant Stenosis

Kumamaru

Kondo

Kumamaru

et al. 2014

Circ: Cardiovascular Imaging

View full text Add to dashboard Cite

Computed Tomography (AUC2010) does not incorporate prior coronary computed tomographic angiography (CCTA) results in the appropriateness of a CCTA examination. The purpose of this study was to explore the criteria for forgoing repeat CCTA among patients with clinical scenarios suggesting CCTA as appropriate after prior CCTA excluding coronary artery disease. Methods and Results-Among patients from a single center (February 2006 to April 2013) who underwent appropriate CCTA based on AUC2010, consecutive 555 CCTAs, which had a prior CCTA excluding significant stenosis (>50% stenosis in diameter), were selected. The median time difference between the studies was 34.2 (Q1-Q3, 22.9-50.1) months. Significant stenosis was detected at the time of repeat scan (by CCTA or subsequent catheter angiography) in 13.3% (74 of 555). A multivariable logistic model (C-statistic, 0.74; bootstrapped overfitting bias, 0.8%) identified 3 predictors of significant stenosis: time difference between the studies >3 years (adjusted odds ratio, 2.1; 95% confidence interval, 1.2-3.5), diabetes mellitus (odds ratio, 2.4; 95% confidence interval,1.4-4.3), and 26% to 50% stenosis on the initial CCTA (odds ratio, 5.6; 95% confidence interval, 3.2-9.6). When these 3 factors were all absent (corresponding to 31.9% of the population), the probability of significant stenosis was 4.5% (95% confidence interval, 2.7-7.4%), whereas 17.1% of patients had significant stenosis among those with at least 1 positive variable. When coronary arteries were completely normal at the initial scan, the prevalence of significant stenosis was only 1.8% irrespective of other factors, and no patient underwent revascularization. Conclusions-Nondiabetic patients with a prior CCTA <3 years showing no or ≤25% stenosis had a <5% prevalence of significant stenosis.

show abstract

Section: Discussionsupporting

confidence: 89%

Repeat Coronary Computed Tomographic Angiography in Patients With a Prior Scan Excluding Significant Stenosis

Kumamaru

Kondo

Kumamaru

et al. 2014

Circ: Cardiovascular Imaging

View full text Add to dashboard Cite

show abstract

“…The overall accuracy of MDCTA observed in our study is in keeping with other single and multicenter trials using 64-slice scanner evaluating patients with chronic stable CAD [3][4][5][6][30][31][32]. In contrast, previous evaluating patients with suspected ACS showed variable results.…”

Section: Diagnostic Accuracy In Patients With Suspected Acssupporting

confidence: 88%

Accuracy of multidetector computed tomography for detection of coronary artery stenosis in acute coronary syndrome compared with stable coronary disease: A CORE64 multicenter trial substudy

Sara

Rochitte

Lemos

et al. 2014

International Journal of Cardiology

View full text Add to dashboard Cite

“…While most data report intermediate follow up times – similar to the nuclear medicine literature – a few long term studies are also available. In a large meta-analysis, the association of cardiac events with CAD evaluation by 64-slice or greater CCTA was analyzed [37]. The study consisted of more than 82,000 patient-years with over 2,000 ‘hard’ events.…”

Section: Prognostic Value Of Cctamentioning

confidence: 99%

Cardiac CT vs. Stress Testing in Patients with Suspected Coronary Artery Disease: Review and Expert Recommendations

Rahsepar

Arbab‐Zadeh

2015

Curr Cardiovasc Imaging Rep

View full text Add to dashboard Cite

Diagnosis and management of coronary artery disease represent a major challenge to our health care systems affecting millions of patients each year. Until recently, the diagnosis of coronary artery disease could be conclusively determined only by invasive coronary angiography. To avoid risks from cardiac catheterization, many healthcare systems relied on stress testing as gatekeeper for coronary angiography. Advancements in cardiac computed tomography angiography technology now allows to noninvasively visualize coronary artery disease, challenging the role of stress testing as the default noninvasive imaging tool for evaluating patients with chest pain. In this review, we summarize current data on the clinical utility of cardiac computed tomography and stress testing in stable patients with suspected coronary artery disease.

show abstract

Association of cardiac events with coronary artery disease detected by 64-slice or greater coronary CT angiography: A systematic review and meta-analysis

Cited by 47 publications

References 59 publications

Repeat Coronary Computed Tomographic Angiography in Patients With a Prior Scan Excluding Significant Stenosis

Repeat Coronary Computed Tomographic Angiography in Patients With a Prior Scan Excluding Significant Stenosis

Accuracy of multidetector computed tomography for detection of coronary artery stenosis in acute coronary syndrome compared with stable coronary disease: A CORE64 multicenter trial substudy

Cardiac CT vs. Stress Testing in Patients with Suspected Coronary Artery Disease: Review and Expert Recommendations

Contact Info

Product

Resources

About