“…As compared to other inflammatory nontumoral conditions and as quantified with SUVmax, lung 18 F-FDG uptake of patients with ACS (median 2.5 [0.6–1.0]) was in the range of that reported in patients having lung contusion (2.2) 24 or idiopathic pulmonary fibrosis (2.8), 23 but lower than that reported in the pulmonary parenchyma of patients with sarcoidosis (5.1). 25 Lung 18 F-FDG uptake has been associated with lung neutrophilic inflammation in various conditions of acute lung injury, including experimental models of pneumococcal pneumonia, 9 , 26 bleomycin pneumonitis, 9 , 26 endotoxemia, 27 , 28 ventilator-induced lung injury, 12 smoke inhalation, 29 and airway instillation of endotoxin in humans. 11 Because increased bronchoalveolar fluid neutrophilia has been reported during ACS, 8 one can hypothesize that neutrophils are the main cells accounting for lung 18 F-FDG uptake during ACS.…”