Cancer incidence varies significantly depending on Sasang constitution of Traditional Korean Medicine

Lee, Jonghoon; Kang, Weechang; Cho, Junghyo; Cho, Chong-Kwan; Yoo, Hwa‐Seung; Son, Chang-Gue

doi:10.1016/s0254-6272(13)60171-5

Cited by 11 publications

(7 citation statements)

References 17 publications

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“…Oxidative stress is implicated in diverse pathophysiological conditions, including inflammation, neurodegenerative diseases, and cancer [ 29 ]. Our previous study found that the incidence of cancer was significantly lower in Taeumins than in Soumins or Soyangins [ 30 ]. The serum cortisol levels however would be affected by time point of blood sample because circadian rhythm in the release of cortisol and adrenaline is well known [ 31 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

Serum Levels of Stress Hormones and Oxidative Stress Biomarkers Differ according to Sasang Constitutional Type

Kim

Ahn

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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Objectives. This study investigated whether Sasang constitutional type is associated with differences in the serum levels of stress hormones and oxidative stress. Methods. A total of 236 participants (77 males and 159 females) were enrolled. The serum levels of cortisol, adrenaline, reactive oxygen species (ROS), and malondialdehyde (MDA) were analyzed. Results. The distribution of Sasang constitutional types was as follows: Taeumin, 35.6%; Soumin, 33.0%; and Soyangin, 31.4%. The serum cortisol levels of Taeumin were significantly lower than Soumin (p < 0.1 in both sexes) and Soyangin (p < 0.05 in males and p < 0.1 in females). The adrenaline levels were also significantly lower in Taeumin than in Soumin (p < 0.05 in males and p < 0.1 in females) and Soyangin (p < 0.1 in males). Serum ROS levels were significantly higher in Soyangin than in Taeumin and Soumin (p < 0.05 in males), whereas MDA levels were significantly lower in Taeumin compared with Soumin and Soyangin (p < 0.05 in males and p < 0.1 in females). Conclusion. Taeumin type may tolerate psychological or oxidative stress better than other types, which suggests a biological mechanism to explain the different pathophysiological features of Sasang constitutional types.

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Section: Discussionmentioning

confidence: 99%

Serum Levels of Stress Hormones and Oxidative Stress Biomarkers Differ according to Sasang Constitutional Type

Kim

Ahn

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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“…Sex-related differences in the development of various diseases are well known [ 31 ]. Our previous study found a significant difference in cancer prevalence according to Sasang classification and gender, with higher cancer prevalence in Soumin-type males and Soyangin-type females [ 32 ]. These findings would recommend the Sasang constitution as an important medicine in diagnosis or therapeutics of FD.…”

Section: Discussionmentioning

confidence: 99%

Sasang constitution affects the prevalence of functional dyspepsia

Kim

Ahn

Son

2015

BMC Complement Altern Med

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BackgroundFunctional dyspepsia (FD), which is a very common disorder worldwide, is known to be caused by multiple factors including environmental and genetic factors. Sasang constitutional medicine (SCM) is a component of traditional Korean medicine that emphasizes inherited characteristics of the physical and psychological patterns of a patient. This study investigated whether the prevalence of FD differs depending on Sasang classification.MethodsA total 517 subjects (190 males and 327 females) were recruited, and interviewed for the presence of FD using a Rome III-based questionnaire. The Sasang constitution of all subjects were diagnosed using a Sasang constitutional analytical tool (SCAT). A Chi-square test was performed to compare prevalence of DF among different Sasang constitutional types.ResultsOf the 517 subjects, 115 (22.2 %) met the diagnostic criteria for FD, and the prevalence was significantly higher in females (26.9 %) than males (14.2 %, p < 0.01). The Sasang-constitution-based prevalence among all subjects was 27.5 % for Taeumin, 23.1 % for Soumin, and 16.4 % for Soyangin (p = 0.055). When compared by sex, the prevalence of FD among Sasang types showed significantly different patterns between males and females (p < 0.05); in females with FD, Taeumin predominated (32.5 % compared with 29.5 % and 18.8 % for Soumin and Soyangin, respectively; p < 0.05), whereas males with FD displayed a higher prevalence of Soumin (17.3 % compared with 9.1 % and 11.3 % for Taeumin and Soyangin, respectively; p > 0.05).ConclusionsThis study identified significant differences in FD prevalence depending on Sasang constitution and sex. Our findings provide data to guide future research on the prevention and management of FD.

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“…Ahn performed an association study to compare subclinical hypothyroidism and the Sasang constitutions (Ahn et al, 2012). Lee showed that cancer incidence varied significantly based on the Sasang constitution (Lee et al, 2013c). Kim and Sok studied the health management of older Korean adults based on the four constitutions (Kim and Sok, 2012).…”

Section: Somatotype Characteristicsmentioning

confidence: 99%

Recent progress and prospects in Sasang constitutional medicine: A traditional type of physiome-based treatment

Kim¹,

Noble²

2014

Progress in Biophysics and Molecular Biology

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Cancer incidence varies significantly depending on Sasang constitution of Traditional Korean Medicine

Abstract: This study identified a trend involving the frequency of cancer and the Sasang constitutional classification. We hope that this finding will provide new ideas for the study of cancer incidence and its preventive management.

Cited by 11 publications

References 17 publications

Serum Levels of Stress Hormones and Oxidative Stress Biomarkers Differ according to Sasang Constitutional Type

Serum Levels of Stress Hormones and Oxidative Stress Biomarkers Differ according to Sasang Constitutional Type

Sasang constitution affects the prevalence of functional dyspepsia

Recent progress and prospects in Sasang constitutional medicine: A traditional type of physiome-based treatment

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