240. Stellungnahme des DZK in Zusammenarbeit mit FZB, DGI, DGPI, GPP, DGGG, DRG und DGMP zum Tuberkulosescreening bei Schwangeren im Kontext von § 36 (4) Infektionsschutzgesetz (IfSG)

Seelbach-Göbel, B; Beckmann, Matthias W.

doi:10.1055/s-0042-123082

Cited by 2 publications

(6 citation statements)

References 14 publications

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“…CT scans are contraindicated in pregnancy; however, one single X-ray image in patients in whom there is reasonable suspicion (e.g. persistent cough) can be performed without a risk to the foetus 28 and is recommended in Germany whenever corresponding symptoms are present 29 .…”

Section: Reviewmentioning

confidence: 99%

“…Tests that can be used to detect the presence of pathogens include IFN-γ release assays (IGRA) (e.g. QuantiFERON test) or the classic tuberculin skin test (TST, also known as the Mendel-Mantoux test), which is also safe during pregnancy 29 . There is no concrete information on the sensitivity and specificity of TST and IGRA testing in pregnancy.…”

Section: Reviewmentioning

confidence: 99%

“…However, and as previously described, it is assumed that pregnant women are at an increased risk of progression or reactivation of a latent tuberculosis infection all the way to a manifest and potentially contagious disease. For this reason, the German Central Committee Against Tuberculosis (DZK), in collaboration with the German Society of Gynecology and Obstetrics (DGGG), generally recommends preferably using an IGRA for screening in pregnant, asylum-seeking women 29 . In case of a positive test result, this should in any case be followed by a chest X-ray.…”

Section: Reviewmentioning

confidence: 99%

“…Letzteres ist in der Schwangerschaft kontraindiziert, allerdings kann ein einzelnes Röntgenbild bei begründetem Verdacht (z. B. anhaltender Husten) ohne Gefahr für den Fetus erfolgen 28 und ist bei entsprechenden Symptomen in Deutschland empfohlen 29 .…”

Section: Klinik Diagnostik Und Therapie Der Tuberkulose In Der Schwaunclassified

“…B. QuantiFERON-Test) oder der klassische Tuberkulin-Hauttest (THT, sog. Mendel-Mantoux-Test), der auch in der Schwangerschaft sicher anwendbar ist 29 . Konkrete Angaben zu Sensitivität und Spezifität von THT und IGRA in der Schwangerschaft fehlen.…”

Section: Präventionunclassified

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Tuberculosis in Pregnancy – a Summary

Wolf

Krasselt

Fallois

et al. 2019

Geburtshilfe Frauenheilkd

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In recent years, the incidence of tuberculosis in pregnancy in the industrialised countries has increased. Tuberculosis in pregnancy is associated with an increased risk for the mother and child. Even if no figures are available for Germany, an increase in the number of tuberculosis cases among pregnant women can be assumed due to the migratory flows; current data from the USA, for example, also show an increasing incidence of tuberculosis in pregnant women in recent years. The physiological and immunological changes that occur during pregnancy are likely to have a negative impact on the course of the disease and may make it more difficult to confirm the diagnosis. There are no internationally standardised recommendations for diagnosing latent tuberculosis infections. When screening for TB is performed in specific risk populations, an Interferon-γ Release Assay (IGRA) should preferably be carried out according to the current study data. If corresponding symptoms are present and an IGRA test is positive, further diagnostics are indicated, also in pregnancy. If tuberculosis is confirmed, the fact that a woman is pregnant must not delay the initiation of anti-tuberculosis therapy, as an early start of therapy is associated with a more favourable outcome for both mother and child. The common first-line therapeutic drugs may also be used during pregnancy and are considered safe. The treatment of latent tuberculosis during pregnancy is disputed.

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Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

Section: Klinik Diagnostik Und Therapie Der Tuberkulose In Der Schwaunclassified

Section: Präventionunclassified

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Tuberculosis in Pregnancy – a Summary

Wolf

Krasselt

Fallois

et al. 2019

Geburtshilfe Frauenheilkd

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The Diagnosis and Treatment of Tuberculosis

Suárez¹,

Fünger²,

Kröger³

et al. 2019

Deutsches Ärzteblatt International

144

104

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Refugees and asylum seekers are defined in many ways but can be considered as those who did not make a voluntary choice to leave their country of origin and cannot return home in safety. Outcome data are limited and mostly focused on perinatal and mental health but do suggest significant levels of unmet need. This scoping review considered 72 studies where refugees and asylum seekers formed part or all of the population studied. Access to appropriate health care across the WHO European Region is very varied and is overwhelmingly shaped by legal frameworks and the regulation of the migration process. The need for improved communication with asylum seekers and coordinated action between agencies within and beyond the medical system is widely noted. Improved data to support intersectoral working to address the health care needs of asylum seekers and refugees are imperative.

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240. Stellungnahme des DZK in Zusammenarbeit mit FZB, DGI, DGPI, GPP, DGGG, DRG und DGMP zum Tuberkulosescreening bei Schwangeren im Kontext von § 36 (4) Infektionsschutzgesetz (IfSG)

Cited by 2 publications

References 14 publications

Tuberculosis in Pregnancy – a Summary

Tuberculosis in Pregnancy – a Summary

The Diagnosis and Treatment of Tuberculosis

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