24-Hour Blood Pressure in Uygur, Kazakh and Han Elderly Subjects in China.

Kawamura, Hiroshi; Jumabay, Medet; Mitsubayashi, Hiromi; Izumi, Yasukatsu; Soma, Masayoshi; Ozawa, Yukio; Rehemudula, Duolikun; Mahmut, Masum; Mu, Yuming; Aisa, Muhebul; Cheng, Zu Heng; Wang, Shi Zhen

doi:10.1291/hypres.23.177

Cited by 20 publications

(24 citation statements)

References 9 publications

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“…5,6 In Xinjiang, the Uygur have been shown to have a lower prevalence of hypertension than the Han or Kazakh people, [7][8][9] and in the present study, the elderly Uygur subjects were less hypertensive compared with the general elderly Chinese population. The longevous Uygur subjects were also less hypertensive, so it seems that those who are less hypertensive have an advantage in terms of life expectancy.…”

Section: Centenarians and Hypertensionsupporting

confidence: 45%

Ambulatory Blood Pressure Monitoring in Uygur Centenarians

Jumabay

Ozawa

Kawamura

et al. 2002

Circ J

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t has been shown that the humans living to a very old age have a genetic tendency toward moderate and balanced blood pressure (BP). 1,2 The Uygurs in Xinjiang are a naturally longevous population, surviving to a very old age without any medical treatment or services. There have been studies showing that the Uygur people do live to an older age than other people in the Xinjiang Uygur Autonomous Region of China, 3,4 but these reports have not provided information on the blood pressure (BP) variations, such as the day -night BP differences and the circadian rhythm, in the Uygur centenarians.Noninvasive 24-h ambulatory blood pressure monitoring (ABPM) devices are now commercially available and are often used to overcome the 'white-coat' effect and identify white-coat hypertension when studying the circadian rhythm of BP. A person's ambulatory BP measured during daily life can provide more meaningful information than can recordings of BP taken in the physician's office, and interesting information is provided when this method is used for persons of different ethnicities. Therefore we used ABPM in our study of office and ambulatory BP, pulse rate (PR), prevalence of hypertension, difference between day-and night-time BP and PR, and circadian BP and PR rhythms in Circulation Journal Vol.66, January 2002 centenarian, longevous, and elderly Uygurs. Methods Study PopulationTwo hundred and thirty-six clinically healthy subjects were recruited from Uygur residences by randomized, parallel-design sampling in Hotan, Xinjiang Uygur Autonomous Region, People's Republic of China during July and August 2000. All subjects gave their informed consent to participate. Subjects were divided into 3 groups according to age: a centenarian group (33 subjects, age ≥100 years), a longevous group (103 subjects, age 90-99 years) and an elderly group (100 subjects, age 65-70 years). Elderly and longevous subjects were engaged in physical labor, despite advancing age, but the centenarians only managed their daily physical activities. We confirmed the age of subjects through resident registration forms, and marital, family and personal histories conveyed in the local language. The office BP examination was undertaken at the local hospital. All subjects resided in a dormitory of the health-care center of the village for the 3 days of this investigation. Twentyfour-hour ABPM was conducted in each subject's place of residence and they were asked to maintain their normal schedule of activity and regular rest. A diary of their activities was recorded during the BP monitoring. All subjects were served their usual meals at 07.00, 11.30, and 19.00 h. Subjects underwent other physical examinations after the ABPM ceased. None of the subjects had previously received antihypertensive agents. Office BP and 24-h BP/PR MonitoringThe office BP was determined at the beginning of the Ambulatory Blood Pressure Monitoring in Uygur CentenariansMedet Jumabay, MD; Yukio Ozawa, MD; Hiroshi Kawamura, MD*; Satoshi Saito, MD; Yoichi Izumi, MD; Hiromi Mitsubayashi, MD*...

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Section: Centenarians and Hypertensionsupporting

confidence: 45%

Ambulatory Blood Pressure Monitoring in Uygur Centenarians

Jumabay

Ozawa

Kawamura

et al. 2002

Circ J

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“…Other studies have reported that the Uygur have a lower prevalence of hypertension than the Han or Kazakhs living in the same Region (3,4). However, the Uygur centenarians have been shown a higher incidence of hypertension than the Uygur individuals (aged 65-70 years, candidates for centenarians)…”

Section: Introductionmentioning

confidence: 95%

Time-Series Analysis of Systolic Blood Pressure Variation in Thirty-Three Uygur Centenarians in China

et al. 2003

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(5). There have been only a few studies on ambulatory blood pressure monitoring (ABPM) in centenarians (5-7). Unfortunately, most of these reports have failed to provide time-series analyses of blood pressure variation (BPV) and its parameters-i.e., frequency, period, acrophase, and maximum and minimum values. In particular, there has been no timeseries analysis of BPV on more than thirty centenarians. Accordingly, the purpose of this study was to clarify the role of BPV in the longevity of the Uygur by performing a time-series analysis of BPV in the Uygur centenarians and comparing the results with those for their younger counterparts, Uygur elderly subjects, in Hotan (UEH).

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“…Despite a lack of medical treatment, the Uygurs living in the southern territory of the Xinjiang Uygur Autonomous Region of the People's Republic of China reportedly represent a naturally long-lived population. [1][2][3] Prevalence of hypertension is lower in Uygurs than in other any ethnic group in China. 1 However, our previous study noted that Uygur centenarians demonstrated higher blood pressure (BP) than other elderly subjects on occasional measurement.…”

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confidence: 96%

“…[1][2][3] Prevalence of hypertension is lower in Uygurs than in other any ethnic group in China. 1 However, our previous study noted that Uygur centenarians demonstrated higher blood pressure (BP) than other elderly subjects on occasional measurement. 4 A study of centenarians has shown that 24-h BP values were higher than office BP values, 5 but very limited numbers of centenarians have been studied.…”

mentioning

confidence: 96%