24-h ambulatory blood pressure in 352 normal Danish subjects, related to age and gender*

Wiinberg, Niels; Høegholm, Asbjørn; Christensen, Hanne; Bang, Lia E.; Mikkelsen, Kim Lyngby; Nielsen, Poul Ebbe; Tl, Svendsen; Kampmann, Jens P.; Madsen, N H; Bentzon, Michael Weis

doi:10.1016/0895-7061(95)00216-2

Cited by 362 publications

(276 citation statements)

References 21 publications

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“…This limit is somewhat higher than reported by others; the explanation for this can-apart from the different methodologies-rely on the different populations studied, eg, unlike in mediterranean countries 2 the 'siesta effect' is not discernible in the 24-h BP profiles in the northern European countries. 17 If one accepts the cut-off criterion as suggested from our data, the prevalence of white coat hypertension is approximately 19% among patients with newly diagnosed mild-to-moderate hypertension, a somewhat lower figure than previously reported, 6 but similar to the figures reported by others. 29 It is obvious, though that the frequency of white coat hypertension is declining with more severe office BP elevations at admission, as is illustrated in Table 3, where 135.6/90.4 mm Hg is the cut-off criterion (definition #3 from Table 2).…”

Section: Discussionsupporting

confidence: 86%

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White coat hypertension and target organ involvement: the impact of different cut-off levels on albuminuria and left ventricular mass and geometry

Høegholm¹,

Ks²,

Le³

et al. 1998

J Hum Hypertens

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The aim of this cross-sectional study which took place in a hypertension clinic at a district general hospital in Denmark was to make a pragmatic definition of white coat hypertension. A total of 420 patients were referred consecutively from general practice with newly diagnosed untreated essential hypertension and 146 normal subjects were drawn at random from the Danish national register. The following measurements were taken: office blood pressure; 24-h ambulatory blood pressure (BP) monitoring; echocardiography with determination of left ventricular mass index and relative wall thickness; and early morning urine albumin/creatinine ratios.Four different cut-off levels were studied. An ambul-

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Section: Discussionsupporting

confidence: 86%

“…As part of a multicentre study to establish the distribution of ABP in the population, 17 we performed 24-h BP monitoring in subjects drawn at random from the Danish national register. There was an intended similar number of subjects in different gender and age strata from 20-79 years.…”

Section: Methodsmentioning

confidence: 99%

White coat hypertension and target organ involvement: the impact of different cut-off levels on albuminuria and left ventricular mass and geometry

Høegholm¹,

Ks²,

Le³

et al. 1998

J Hum Hypertens

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“…1 On the other hand, studies investigating the relationship between age and ambulatory BP have yielded conflicting findings, ranging from no change in BP to moderately higher BP as a function of age. [2][3][4][5][6][7] The relationship between gender and age-related BP changes is unclear, as most studies do not report on the association between these variables. In a meta-analysis of 23 ambulatory studies including subjects between the ages of 17-80, Staessen and colleagues 8 reported that SBP increases on the average 2.8 mm Hg per decade in women, but only 0.2 mm Hg per decade in men, whereas DBP increases 1.1 mm Hg per decade in both men and women.…”

Section: Introductionmentioning

confidence: 99%

Effects of age and gender on ambulatory blood pressure and heart rate

Jaquet

Shapiro

1998

J Hum Hypertens

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In a large group of young (n = 194) and elderly (n = 148) healthy subjects, we explored the relationship between ambulatory blood pressure (BP) levels, within-subject BP variability, and age in men and women. The questions asked were: Do elderly subjects display higher BP levels and variability compared to a young group? Are there gender differences in BP level and variability? Are these gender differences similar in the young and the elderly subjects? Do age or gender influence BP in a similar way during waking and during sleep? Subjects wore an ambulatory BP monitor (Accutracker II) for 24 h.

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“…[34][35][36] The 'white coat effect' can be easily detected as well as white coat hypertension. It has been shown that subjects with ISH are characterised by a higher variability of BP, high prevalence of white coat effect and postprandial fall.…”

Section: Epidemiologymentioning

confidence: 99%

Isolated systolic hypertension: pathophysiology, consequences and therapeutic benefits

et al. 1998

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During recent decades the importance of perceiving isolated systolic hypertension (ISH) in cardiovascular pathophysiology has been changed from a benign condition to the major cardiovascular risk factor. Aging is per se associated with the deterioration in arterial compliance through both structural and functional changes in large arteries which mainly involves the intima and media. The observed changes result in a decrease of the lumen-to-wall ratio, the overall lumen cross-sectional area and an increase of arterial stiffness which especially involve the aorta and other elastic arteries. In addition to the structural changes in vessel walls, aging is associated with certain functional changes such as an increase in sympathetic system activity probably due to the age-related decreased sensitivity of beta-receptors. While the function of arterial wall alpha-receptors remains intact, in elderly subjects a shift towards arterial vasoconstriction can be observed.

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24-h ambulatory blood pressure in 352 normal Danish subjects, related to age and gender*

Cited by 362 publications

References 21 publications

White coat hypertension and target organ involvement: the impact of different cut-off levels on albuminuria and left ventricular mass and geometry

White coat hypertension and target organ involvement: the impact of different cut-off levels on albuminuria and left ventricular mass and geometry

Effects of age and gender on ambulatory blood pressure and heart rate

Isolated systolic hypertension: pathophysiology, consequences and therapeutic benefits

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