2013
DOI: 10.1007/s00198-013-2486-3
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Association of volumetric bone mineral density with abdominal aortic calcification in African ancestry men

Abstract: PURPOSE To assess the prevalence and correlates of abdominal aortic calcification (AAC) in a sample of 278 Afro-Caribbean men (mean age 56) and to test for a largely unexplored association between cortical and trabecular volumetric bone mineral density (vBMD) with AAC prevalence. METHODS Men were recruited consecutively as part of an ongoing prospective cohort study of body composition in men aged 40+. For this analysis, AAC was assessed by computed tomography of the abdomen from L3 to S1. Aortic calcium was… Show more

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Cited by 13 publications
(21 citation statements)
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“…Additional segmentations of the psoas and paraspinous skeletal muscles were performed and corresponding volumes of fat and lean tissue calculated within a 30‐mm block of slices centered at L3‐4. Calcified atherosclerotic plaque was measured in the infrarenal abdominal aorta and common iliac arteries and reported as an Agatston score (Aquarius Workstation, TeraRecon, Foster City, CA, USA), as previously described …”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Additional segmentations of the psoas and paraspinous skeletal muscles were performed and corresponding volumes of fat and lean tissue calculated within a 30‐mm block of slices centered at L3‐4. Calcified atherosclerotic plaque was measured in the infrarenal abdominal aorta and common iliac arteries and reported as an Agatston score (Aquarius Workstation, TeraRecon, Foster City, CA, USA), as previously described …”
Section: Methodsmentioning
confidence: 99%
“…The same methods employed for morphometric assessment of Calcified atherosclerotic plaque was measured in the infrarenal abdominal aorta and common iliac arteries and reported as an Agatston score (Aquarius Workstation, TeraRecon, Foster City, CA, USA), as previously described. 24,26,27…”
Section: Morphometric Measuresmentioning
confidence: 99%
“…However, calcification begins in the larger arteries and then progresses to the smaller arteries [49,50], so our findings may largely reflect the earlier stage of vascular disease present in our population sample. Indeed, the prevalence of vascular calcification in these African ancestry men is lower than those seen in similarly aged US Caucasian and African American samples [51]. This is also the probable explanation for why BMI and waist circumference were the only measures associated with CAC in fully adjusted models.…”
Section: Discussionmentioning
confidence: 99%
“…The diagnosis of osteoporosis depends on area bone mineral density (BMD) measurements using dual energy X-ray absorptiometry (DXA) [ 2 ]. BMD has been inversely associated with subclinical and clinical cardiovascular disease (CVD), even after adjusting for potential confounding factors [ 3 ]. Previous studies have examined the relationship between trabecular volumetric BMD (vBMD) and aortic arterial calcification (AAC) or coronary artery calcification (CAC), with inconclusive results [ 3 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…BMD has been inversely associated with subclinical and clinical cardiovascular disease (CVD), even after adjusting for potential confounding factors [ 3 ]. Previous studies have examined the relationship between trabecular volumetric BMD (vBMD) and aortic arterial calcification (AAC) or coronary artery calcification (CAC), with inconclusive results [ 3 6 ]. Cortical, but not trabecular, vBMD was associated with significantly decreased odds of AAC prevalence independent of other traditional risk factors [ 3 ].…”
Section: Introductionmentioning
confidence: 99%