Community-Wide Distribution of Long-Lasting Insecticidal Nets Can Halt Transmission of Lymphatic Filariasis in Southeastern Nigeria

Richards, Frank O.; Emukah, Emmanuel; Graves, Patricia M.; Nkwocha, Omeni; Nwankwo, Lawrence; Rakers, Lindsay; Mosher, Aryc W.; Patterson, Amy E.; Ozaki, Masayo; Nwoke, Beb; Ukaga, CN; Njoku, Chidiebere; Nwodu, Kenrick; Obasi, Andrew; Miri, Emmanuel S.

doi:10.4269/ajtmh.12-0775

Cited by 41 publications

(37 citation statements)

References 22 publications

(21 reference statements)

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“…The 2010/2011 LLIN distribution had a significant impact on our entomological findings in the SVs. These findings mirror those reported in an LLIN-only approach utilized in south-east Nigeria, where the program area experienced a statistically significant decrease in LF infection and infectivity [4]. Entomologically, it became evident in the SVs that LF transmission was completely interrupted after 2010.…”

Section: Discussionsupporting

confidence: 79%

Long-Lasting Insecticidal Nets Are Synergistic with Mass Drug Administration for Interruption of Lymphatic Filariasis Transmission in Nigeria

et al. 2013

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In central Nigeria Anopheles mosquitoes transmit malaria and lymphatic filariasis (LF). The strategy used for interrupting LF transmission in this area is annual mass drug administration (MDA) with albendazole and ivermectin, but after 8 years of MDA, entomological evaluations in sentinel villages showed continued low-grade mosquito infection rates of 0.32%. After long-lasting insecticidal net (LLIN) distribution by the national malaria program in late 2010, however, we were no longer able to detect infected vectors over a 24-month period. This is evidence that LLINs are synergistic with MDA in interrupting LF transmission.

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Section: Discussionsupporting

confidence: 79%

Long-Lasting Insecticidal Nets Are Synergistic with Mass Drug Administration for Interruption of Lymphatic Filariasis Transmission in Nigeria

et al. 2013

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“…However, the very high bed net coverage noted in 2011 was somehow inflated, due to the free household distribution of ITNs, and it declined to some extent afterwards. Bed net use can be an important supportive measure for LF control [48][49][50], but it is necessary to invest efforts in motivating and engaging people in correct usage of the nets to give optimal health benefits. Otherwise many nets will be transformed into other useful appliances during the seasons with low mosquito densities.…”

Section: Discussionmentioning

confidence: 99%

Lymphatic filariasis control in Tanga Region, Tanzania: status after eight rounds of mass drug administration

Simonsen

Derua

Magesa

et al. 2014

Parasites & Vectors

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LF was still widespread in many parts of Tanga Region after MDA 8, in particular in the coastal areas. This calls for intensified control, which should include increased MDA treatment coverage, strengthening of bed net usage, and more male focus in LF health information dissemination. The low LF burdens observed in some inland districts suggest that MDA in these could be stepped down to provide more resources for upscale of control in the coastal areas. Monitoring should continue to guide the programme to ensure that the current major achievements will ultimately lead to successful LF elimination.

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“…Whilst bed nets have the potential to interrupt transmission without the need for MDA (Richards et al . ), this requires a high geographical coverage of bed nets, plus the nets need to be used consistently and correctly, and as such, WHO currently recommends MDA as the primary method for interrupting transmission (WHO ; WHO and Global Programme to Eliminate Lymphatic Filariasis ). With regard to the assumption regarding MDA for onchocerciasis, whilst there is evidence that this has impacted LF transmission (Kyelem et al .…”

Section: Resultsmentioning

confidence: 99%

Quantifying filariasis and malaria control activities in relation to lymphatic filariasis elimination: a multiple intervention score map (MISM) for Malawi

Stanton

Mkwanda

Mzilahowa

et al. 2014

Tropical Med Int Health

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Abstractobjective To quantify the geographical extent of filariasis and malaria control interventions impacting lymphatic filariasis (LF) in Malawi and to produce a multiple intervention score map (MISM) for prioritising surveillance and intervention strategies.methods Interventions included mass drug administration (MDA) for LF and onchocerciasis, and bed nets and indoor residual spraying (IRS) for malaria. District and subdistrict-level data were obtained from the Ministry of Health in Malawi, the Demographic and Health Survey (DHS) and President's Malaria Initiative reports. Single intervention scores were calculated for each variable based on population coverage thresholds, and these were combined in a weighted sum to form a multiple intervention score, which was then used to produce maps, that is MISMs. Districts were further classified into four groups based on the combination of their baseline LF prevalence and multiple intervention score.results The district-and subdistrict-level MISMs highlighted specific areas that have received high and low coverage of LF-impacting interventions. High coverage areas included the LF-onchocerciasis endemic areas in the southern region of the country and areas along the shores of Lake Malawi, where malaria vector control had been prioritised. Three districts with high baseline LF prevalence measures but low coverage of multiple interventions were identified and considered to be most at risk of ongoing transmission or re-emergence.conclusions These maps and district classifications will be used by LF programme managers to identify and target high-risk areas that may not have received adequate LF-impacting interventions to interrupt the transmission of the disease.

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Community-Wide Distribution of Long-Lasting Insecticidal Nets Can Halt Transmission of Lymphatic Filariasis in Southeastern Nigeria

Cited by 41 publications

References 22 publications

Long-Lasting Insecticidal Nets Are Synergistic with Mass Drug Administration for Interruption of Lymphatic Filariasis Transmission in Nigeria

Long-Lasting Insecticidal Nets Are Synergistic with Mass Drug Administration for Interruption of Lymphatic Filariasis Transmission in Nigeria

Lymphatic filariasis control in Tanga Region, Tanzania: status after eight rounds of mass drug administration

Quantifying filariasis and malaria control activities in relation to lymphatic filariasis elimination: a multiple intervention score map (MISM) for Malawi

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