Consequences of Interstitial Cystitis/Bladder Pain Symptoms on Women's Work Participation and Income: Results from a National Household Sample

Beckett, Megan K.; Elliott, Marc N.; Clemens, J. Quentin; Ewing, Brett; Berry, Sandra H.

doi:10.1016/j.juro.2013.07.018

Cited by 21 publications

(25 citation statements)

References 11 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Participants who experienced these types of flares reported difficulties completing their education, quitting or losing their jobs, relationship strain, and anxiety. Although these consequences are similar to those reported for UCPPS in general in both our study and the literature [20–22, 13, 23–28], some participants attributed these consequences directly to flares, suggesting that one useful way to improve their quality of life would be to identify approaches to prevent or treat their flares, or to reduce the severity, duration, and/or frequency of their flares (e.g., through the longer-term effects of medications). Together with findings on the immediate impact of flares and those from our previous survey [9], these results also suggest that flare characteristics, such as symptom severity, duration, and frequency, as well as their degree of disruption or bother, should be taken into consideration in developing patient-centered outcome measures of flare burden.…”

Section: Discussionsupporting

confidence: 92%

Urological chronic pelvic pain syndrome flares and their impact: qualitative analysis in the MAPP network

Sutcliffe¹,

Bradley

Clemens

et al. 2015

Int Urogynecol J

Self Cite

View full text Add to dashboard Cite

Introduction Although in-depth qualitative information is critical for understanding patients’ symptom experiences and for developing patient-centered outcome measures, only one previous qualitative study has assessed urologic chronic pelvic pain syndrome (UCPPS) symptom exacerbations (“flares”). Methods We conducted eight focus groups of female UCPPS (interstitial cystitis/bladder pain syndrome) patients at four sites of the MAPP Research Network (n=57, mean=7/group) to explore the full spectrum of flares and their impact on patients’ lives. Results Flare experiences were common and varied widely in terms of UCPPS symptoms involved, concurrent non-pelvic symptoms (e.g., diarrhea), symptom intensity (mild to severe), duration (minutes to years), and frequency (daily to

show abstract

Section: Discussionsupporting

confidence: 92%

Urological chronic pelvic pain syndrome flares and their impact: qualitative analysis in the MAPP network

Sutcliffe¹,

Bradley

Clemens

et al. 2015

Int Urogynecol J

Self Cite

View full text Add to dashboard Cite

show abstract

“…The QOL is negatively affected by HSB symptoms; patients had lower economic status, painful sex and sleep disorders . Bladder pain, depressive symptoms, physical disability, comorbidities and less work participation were related to each other …”

Section: Diagnosismentioning

confidence: 99%

“…58 Bladder pain, depressive symptoms, physical disability, comorbidities and less work participation were related to each other. 59,60…”

Section: Symptoms and Qolmentioning

confidence: 99%

Clinical guidelines for interstitial cystitis and hypersensitive bladder updated in 2015

Ueda²,

et al. 2016

View full text Add to dashboard Cite

Clinical guidelines for interstitial cystitis and hypersensitive bladder have been updated as of 2015. The guidelines define interstitial cystitis by the presence of hypersensitive bladder symptoms (discomfort, pressure or pain in the bladder usually associated with urinary frequency and nocturia) and bladder pathology, after excluding other diseases explaining symptoms. Interstitial cystitis is further classified by bladder pathology; either Hunner type interstitial cystitis with Hunner lesions or non-Hunner type interstitial cystitis with mucosal bleeding after distension in the absence of Hunner lesions. Hypersensitive bladder refers to a condition, where hypersensitive bladder symptoms are present, but bladder pathology or other explainable diseases are unproven. Interstitial cystitis and hypersensitive bladder severely affect patients' quality of life as a result of disabling symptoms and/or comorbidities. Reported prevalence suggestive of these disorders varies greatly from 0.01% to >6%. Pathophysiology would be an interaction of multiple factors including urothelial dysfunction, inflammation, neural hyperactivity, exogenous substances and extrabladder disorders. Definite diagnosis of interstitial cystitis and hypersensitive bladder requires cystoscopy with or without hydrodistension. Most of the therapeutic options lack a high level of evidence, leaving a few as recommended therapeutic options.

show abstract

“…The aetiology of these conditions, collectively referred to as urological chronic pelvic pain syndrome (UCPPS), is unknown and both are difficult to diagnose and treat [1,2]. The conditions occur in~1-7% of the population [3][4][5][6], and contribute to significant reductions in physical and mental health, sexual health and work productivity, as well as considerable personal and societal healthcare expenditures [4,[7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

A longitudinal analysis of urological chronic pelvic pain syndrome flares in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network

et al. 2019

View full text Add to dashboard Cite

ResultsOf the 385 eligible participants, 24.2% reported no flares, 22.9% reported one flare, 28.3% reported 2-3 flares, and 24.6% reported ≥4 flares, up to a maximum of 18 during the 11-month follow-up (median incidence rate = 0.13/bi-weekly assessment, range = 0.00-1.00). Pelvic pain (mean = 2.63point increase) and urological symptoms (mean = 1.72) were both significantly worse during most flares (60.6%), with considerable within-participant variability (26.2-37.8%). Flare duration varied from 1 to 150 days (94.3% within-participant variability). In adjusted analyses, flares were more common, symptomatic, and/or longer-lasting in women and in those with worse non-flare symptoms, bladder hypersensitivity, and chronic overlapping pain conditions. ConclusionIn this foundational flare study, we found that pelvic pain and urological symptom flares were common, but variable in frequency and manifestation. We also identified subgroups of participants with more frequent, symptomatic, and/or longerlasting flares for targeted flare management/prevention and further study.Longitudinal analysis of UCPPS flares ‡ ‡ Adjusted for site, sex, age, average non-flare symptom intensity, bladder hypersensitivity and number of COPCs, as appropriate. § § Seven extrapelvic regions (back, head, right leg, left leg, right arm, left arm and trunk) were created similarly to previous analyses, using data from the Body Pain Inventory.

show abstract

Consequences of Interstitial Cystitis/Bladder Pain Symptoms on Women's Work Participation and Income: Results from a National Household Sample

Cited by 21 publications

References 11 publications

Urological chronic pelvic pain syndrome flares and their impact: qualitative analysis in the MAPP network

Urological chronic pelvic pain syndrome flares and their impact: qualitative analysis in the MAPP network

Clinical guidelines for interstitial cystitis and hypersensitive bladder updated in 2015

A longitudinal analysis of urological chronic pelvic pain syndrome flares in the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network

Contact Info

Product

Resources

About