The Association between BMI and COPD: The Results of Two Population-based Studies in Guangzhou, China

Abstract

Low BMI was not only a systemic consequence of COPD but also an important risk factor for the development of COPD, which raises the possibility that early intervention in subjects with low BMI may reduce the incidence of COPD.

A study to assess nutritional profile in chronic obstructive pulmonary disease patients

“…BMI doesn't correlate with severity of disease. This is in agreement with Karadag F et al and Yumin Zhou et al 5,6 There was highly significant difference was seen in mid arm circumference between COPD cases and control group (p<0.001). But there was a significant difference between moderate to severe and very severe and no significance observed between severe to very severe group of COPD patients.…”

Body size and physical activity in relation to incidence of chronic obstructive pulmonary disease

“…Data regarding obese values of BMI in relation to COPD were not presented in those studies. 8,9 Inverse associations between physical activity and risk of COPD have been previously reported from a Danish cohort 10 and a Japanese case-control study.…”

“…5 Previous data on BMI and COPD incidence are limited to 2 small studies. 8,9 One prospective study from China 8 reported an increased risk of COPD among people with BMI values less than 18.5 (RR 2.88, 95% CI 1.06-7.85) compared with BMI values of 18.5 or greater. In contrast, when modelling BMI as a continuous variable, a significant positive association between BMI and COPD was observed in that study 8 (RR [per 1-unit BMI increase] 1.14, 95% CI 1.02-1.26).…”

“…8,9 One prospective study from China 8 reported an increased risk of COPD among people with BMI values less than 18.5 (RR 2.88, 95% CI 1.06-7.85) compared with BMI values of 18.5 or greater. In contrast, when modelling BMI as a continuous variable, a significant positive association between BMI and COPD was observed in that study 8 (RR [per 1-unit BMI increase] 1.14, 95% CI 1.02-1.26). One retrospective US study 9 observed an increased risk of COPD among people with BMI values below 24.3 (RR 2.76, 95% CI 1.15-6.59) compared with BMI values of 26.6 or greater.…”

Association of Serum Uric Acid and ADA Levels in an Obese With or Without Metabolic Syndrome

“…The Public around the world paying attention to the prevalence of Obesity 1 due to its association with chronic diseases like breast cancer 2 , COPD 3 and soon. In human beings serum Uric acid is end product of purine metabolism 4 .…”