Abstract:These findings indicate that preoperative topical lidocaine application may be helpful in attenuating airway-circulatory reflexes in laryngeal microscopic surgery.
“…They found that lidocaine exaggerated findings associated with laryngomalacia and resulted in a higher laryngomalacia score, when compared to normal saline controls. However, Arslan et al demonstrated preserved laryngeal patency and closure in adults . Three studies reported that topical lidocaine reduced upper airway reflexes (cough, mechanoreceptor reflexes, and genioglossus muscle activity) during obstructive apnea and impaired the arousal response .…”
Section: Resultsmentioning
confidence: 99%
“…However, Arslan et al demonstrated preserved laryngeal patency and closure in adults. 7 Three studies reported that topical lidocaine reduced upper airway reflexes (cough, mechanoreceptor reflexes, and genioglossus muscle activity) during obstructive apnea and impaired the arousal response. [8][9][10] One study demonstrated that 4% lignocaine reduced upper airway reflex sensitivity for up to 100 minutes.…”
Studies assessing the effect of anesthesia on the upper airway in patients with and without OSA are limited, and few compare effects between agents. Medications with minimal effect on respiratory control (e.g., dexmedetomidine) may work best for DISE.
“…They found that lidocaine exaggerated findings associated with laryngomalacia and resulted in a higher laryngomalacia score, when compared to normal saline controls. However, Arslan et al demonstrated preserved laryngeal patency and closure in adults . Three studies reported that topical lidocaine reduced upper airway reflexes (cough, mechanoreceptor reflexes, and genioglossus muscle activity) during obstructive apnea and impaired the arousal response .…”
Section: Resultsmentioning
confidence: 99%
“…However, Arslan et al demonstrated preserved laryngeal patency and closure in adults. 7 Three studies reported that topical lidocaine reduced upper airway reflexes (cough, mechanoreceptor reflexes, and genioglossus muscle activity) during obstructive apnea and impaired the arousal response. [8][9][10] One study demonstrated that 4% lignocaine reduced upper airway reflex sensitivity for up to 100 minutes.…”
Studies assessing the effect of anesthesia on the upper airway in patients with and without OSA are limited, and few compare effects between agents. Medications with minimal effect on respiratory control (e.g., dexmedetomidine) may work best for DISE.
“…However, it should still be noted that even brief gentle laryngoscopy and topical anesthesia can cause laryngospasm and subsequent airway collapse. [ 20 , 21 ]…”
Securing the airway in patients undergoing surgical intervention to control a deep neck infection (DNI) is challenging for anesthesiologists due to the distorted airway anatomy, limited mouth opening, tissue edema, and immobility. It is critical to assess the risk of a potential difficult airway and prepare the most appropriate airway management method.We reviewed our anesthetic experiences managing patients with DNIs, focusing on the need for video-laryngoscope or awake fiberoptic intubation beyond a standard intubation from the anesthesiologist's perspective.When patients had infections in the masticatory space, mouth of floor, oropharyngeal mucosal space, or laryngopharynx, their airways tended to be managed using methods requiring more effort by the anesthesiologists, and more extensive equipment preparation, compared with use of a standard laryngoscope. The degree to which the main lesion influenced the airway anatomy, especially at the level of epiglottis and aryepiglottic fold was related to the airway management method selected.When managing the airways of patients undergoing surgery for DNIs under general anesthesia, anesthesiologists should use imaging with computed tomography to evaluate the preoperative airway status and a comprehensive understanding of radiological findings, comorbidities, and patients’ symptoms is needed.
“…Adult patients submitted to suspension laryngoscopy may also benefit from the use of vagolytic drugs at the beginning of the surgical procedure, especially from high vagal tone, identified in the cardiologic evaluation [9]. As another proposal, it is suggested that deep anesthesia associated with topical lidocaine may reduce the risk of asystole, but data are still limited [15].…”
Transoral laryngeal procedures are considered minimally invasive but may trigger important complications such as severe bradycardia and even asystole mediated by vagal reflex. The literature on this subject is rare. This article aims to review the literature, explain associated mechanisms, establish prophylactic strategies, and highlight the importance of intraoperative safety protocols.
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