The association between hip bone marrow lesions and bone mineral density: a cross-sectional and longitudinal population-based study

Abstract

Hip BMLs were associated with local BMD (hip and femoral neck) but not with spine BMD and these associations vary according to site. BML prevalence and change was low in this study, hence these findings need confirmation. However, we hypothesize that these associations represent a combination of changes related directly to the BML pathology or changes adjacent to the disease process.

Associations between systemic bone mineral density, knee cartilage defects and bone marrow lesions in patients with knee osteoarthritis

“…reported that transient bone marrow edema (TBME) in the foot and ankle was strongly associated with low systemic BMD; however, the sample size in this study was small ( n = 10). Ahedi et al . found that hip BMLs were associated with local BMD (hip and femoral neck) but not with distant spine BMD; however, the prevalence of hip BMLs was low in this study.…”

Hip Shape as a Predictor of Osteoarthritis Progression in a Prospective Population Cohort

“…Modes 2 and 4 appear to be strongly associated with structural changes in the subchondral bone of the hip, which are risk factors for the progression of OA . For instance, at baseline, lower scores of these modes were associated with greater JSN and prevalence of osteophytes, respectively.…”

“…Quantitative assessment of subchondral hip BMLs in STIR MRI images was done using OsiriX software (Mac version, University of Geneva). BMLs were identified as areas of increased signal intensity adjacent to the subchondral bone on the femoral head and/or the acetabulum .…”

“…High cartilage signal was identified as an increase in the signal intensity of the articular cartilage due to increased water content that appears as a bright band in the cartilage either adjacent to a hip BML or at any location on the STIR MRI slice if no BML was present . High cartilage signal was graded as 0 for absent and 1 for present .…”

“…Although OA is a disease of the whole joint, bone and cartilage remain the focus of its clinical manifestation . Structural changes such as bone marrow lesions (BMLs) and cartilage defects are linked with the progression of hip OA . In addition to these, the morphology of the hip can predict the development of hip OA , but most current assessments are semiquantitative and focus on changes in the cartilage and the presence of bony outgrowths .…”