Influence of inflammatory pathway markers on oxidative stress induced by cold stress in intestine of quails

Fu, Jing; Liu, Chun–Peng; Zhang, Ziwei; Xing, Mingwei; Xu, Shiwen

doi:10.1016/j.rvsc.2013.05.006

Cited by 51 publications

(27 citation statements)

References 28 publications

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“…XOD participates in a great part of free radical generation and catalyzes the conversion of hypoxanthine to xanthine, uric acid, and superoxide [27]. MDA is an oxidized lipid metabolite and can be used to measure the level of oxidative stress in an organism [9]. Cd is a pollutant that has caused poisoning in humans in many regions of the world [26], and it takes several weeks to eliminate Cd via kidney.…”

Section: Discussionmentioning

confidence: 99%

Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

et al. 2017

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To investigate the effects of molybdenum (Mo) and/or cadmium (Cd) on antioxidant function and the apoptosis-related genes in duck spleens. Sixty healthy 11-day-old ducks were randomly divided into six groups of 10 ducks (control, low Mo group, high Mo, Cd, low Mo + Cd, and high Mo + Cd groups). All were fed a basal diet containing low or high dietary doses of Mo and/or Cd. Relative spleen weight, antioxidant indices, apoptosis-related gene mRNA expression levels, and ultrastructural changes were evaluated after 120 days. The results showed that the relative spleen weight decreased significantly in the high Mo + Cd treatment group which compared with control group. Malondialdehyde levels increased and xanthine oxidase and catalase activities decreased in the Mo and/or Cd groups compared with levels in the control group. Bak-1 and Caspase-3 expressions were upregulated in the high Mo + Cd group, while Bcl-2 was downregulated. In addition, mitochondrial crest fracture, swelling, vacuolation, deformed nuclei, and karyopyknosis in both Mo + Cd treated groups were more severe than in the other groups. The results suggest that Mo and/or Cd can induce oxidative stress and apoptosis of spleen via effects on the mitochondrial intrinsic pathway. Moreover, the results indicate the two elements have a possible synergistic relationship.

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Section: Discussionmentioning

confidence: 99%

Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

et al. 2017

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“…Another study investigating the effect of cold stress in mice (4°C/4h daily for 7 days) highlighted the role of macrophages in immunosuppression (Sesti-Costa et al, 2012). Additionally, a recent study revealed that acute and chronic cold stress caused intestinal oxidative stress, through nuclear factors and tumor necrosis factors, associated with breakdown of intestinal homeostasis (Fu et al, 2013). These results expand previous reports referring to the effect of cold stress in glutathione peroxidase metabolism, indicating its possible immune-regulatory impact in visceral organs (Carr et al, 1992;Siems et al, 1994).…”

Section: Discussionmentioning

confidence: 99%

Correlation between equine colic and weather changes

Diakakis

Tyrnenopoulou

2018

J Hellenic Vet Med Soc

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The objective of this study is to evaluate the possible correlation between relative humidity/temperature change and equine colic in a specific region of Northern Greece. A study population of 823 adult horses stabled in a 40-km-radius around Thessaloniki, Northern Greece were included in this study; a total of 245 horses, suffering from several types of colic between January 2010 and December 2012 were selected. Metereological data, including temperature (oC) and relative humidity (%) were obtained as 3-hour periodic measurements by the Hellenic National Metereological Service. Statistical analysis was performed using Spearman correlation coefficients in order to assess the relationship between temperature changes, relative humidity changes and equine colic. A positive correlation between temperature change and equine colic was detected during March for the whole 3-year period, while positive correlation was presented during several months of late spring and late fall in specific years. No correlation between changes in relative humidity values and colic was shown. Moreover, a negative correlation between relative humidity and temperature, for temperatures >10°C (rho=-0.568, p<0.01) was found, while, a positive correlation (rho=0.650, p<0.01) between daily temperature difference (ΔT) and relative humidity difference was detected. In this study, abrupt temperature change was proven as a significant risk factor in the development of colic during late spring and fall, in Northern Greece, requiring more vigilant horse owners and equine practitioners. These results suggest that in the future it may be possible to modulate management taking into consideration the current weather conditions, in order to prevent colic episodes.

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“…Although many organs and systems participate in resisting cold stress (Fu et al 2013;Wang et al 2013;Zhao et al 2013), the most effective regulation is to generate heat quickly. Heat can be produced by all body cells through the conversion of metabolic energy into mechanical and thermal energy.…”

Section: Discussionmentioning

confidence: 99%

Gene expression profile analysis of pig muscle in response to cold stress

Dong-jie

Liu

Wang

et al. 2016

Journal of Applied Animal Research

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Low-temperature injury is one of the most significant causes of livestock damage worldwide. To identify genes that respond to cold stress, the transcriptome profile of the skeletal muscle of the Min pig (Sus scrofa) after cold stress was analysed using the deep sequencing technique. One group was raised in the normal environment (18 ± 2°C, n = 3) as the thermos-neutral group; another group was raised in the low-temperature environment (4 ± 2°C, n = 3) as the cold stress group. After 24 h, the gene expression profile of skeletal muscle was analysed. The results showed that the expression levels of 662 genes were significantly up-regulated, and those of 1058 genes were significantly down-regulated in the thermos-neutral and the cold stress groups (P < 0.01). It was found through Gene Ontology analysis that the significantly differently expressed genes were mainly distributed in the cytoplasm, mitochondrion, organelle envelope and ribosomal subunit. They enriched ribosome, fatty acid metabolism, RNA transport and metabolic pathways. It means that cold stress could significantly change the gene expression profile of pig muscle. ARTICLE HISTORY

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Influence of inflammatory pathway markers on oxidative stress induced by cold stress in intestine of quails

Cited by 51 publications

References 28 publications

Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

Correlation between equine colic and weather changes

Gene expression profile analysis of pig muscle in response to cold stress

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