Improved femoral neck BMD in older Finnish women between 2002 and 2010

Uusi‐Rasi, Kirsti; Karinkanta, Saija; Heinonen, Ari; Sievänen, Harri

doi:10.1016/j.maturitas.2013.04.001

Cited by 4 publications

(2 citation statements)

References 32 publications

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“…Trend data available for osteoporosis in the Skåne region, Sweden [26–28], do however not indicate this. More recent studies from other countries including Finland and USA, actually point in the opposite direction with an increasing time trend in bone mineral density (BMD) [29, 30]. A more strict postmenopausal estrogen prescription compared to earlier may have contributed to an increased fracture incidence but this effect is likely small as the incidence is increasing in both men and women.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology and time trends of distal forearm fractures in adults - a study of 11.2 million person-years in Sweden

Jerrhag

Englund

Karlsson

et al. 2017

BMC Musculoskelet Disord

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BackgroundA distal forearm fracture is a very common injury causing both suffering and substantial health care costs. The incidence of this fracture type seemed to increase worldwide until the middle 1980’s, but thereafter most reports have shown stable or decreasing rates. As few large studies have been presented lately we aimed to describe recent epidemiology and time trends of distal forearm fractures in adults. We paid special attention to fractures in working ages as they present challenges in terms of treatment and costs for sick-leave, and have not previously been thoroughly investigated.MethodsBy use of population data from Statistics Sweden and official in- and out-patient register data of men and women (≥17 years) in Sweden (Skåne region), we ascertained distal forearm fractures and estimated age- and sex-specific rates and time-trends from year 1999 to 2010 (11.2 million person-years (py)).ResultsThe total incidence rate was 278 per 100,000 py (31,233 fractures) with 23% higher annual numbers 2010 compared with 1999. An increase in the annual age standardized incidence was found in men, +0.7% per annum (95% confidence interval (CI) 0.1, 1.4), and women, +0.9% (95% CI 0.5, 1.3), driven mainly by an increasing incidence in working ages (17–64 years). Also, expected demographic changes including a 25% population increase may result in 38% more fractures until 2050, compared to 2017.ConclusionsThe incidence of distal forearm fractures in adults in southern Sweden is increasing, mainly driven by an increase in working ages. In combination with expected demographic changes these findings may present substantial challenges for the future.

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Section: Discussionmentioning

confidence: 99%

Epidemiology and time trends of distal forearm fractures in adults - a study of 11.2 million person-years in Sweden

Jerrhag

Englund

Karlsson

et al. 2017

BMC Musculoskelet Disord

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“…Older, scarce data on time trends of BMD in adult or aged cohorts are available for SE (stable BMD from years 1988/1989 to 1998/1999) [31, 32] but none for DK. A recent study from the nearby country of Finland however found increasing BMD in elderly women from year 2002 to 2010 [33], something that previously has been indicated also in the USA (NHANES III 1988/94 to 2005–2008) [34]. In an examination of a non-population-based register of Canadian BMD data in women (from year 1996 to 2006), the decreasing fracture rates were attributed to a secular increase in BMD rather than anti-osteoporotic treatment and increase in BMI [35].…”

Section: Discussionmentioning

confidence: 99%

Recent hip fracture trends in Sweden and Denmark with age-period-cohort effects

et al. 2016

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SummaryThis study used nationwide hip fracture data from Denmark and Sweden during 1987–2010 to examine effects of (birth) cohort and period. We found that time trends, cohort, and period effects were different in the two countries. Results also indicated that hip fracture rates may increase in the not so far future.IntroductionThe reasons for the downturn in hip fracture rates remain largely unclear but circumstances earlier in life seem important.MethodsWe ascertained hip fractures in the populations ≥50 years in Denmark and Sweden in national discharge registers. Country- and sex-specific age-period-cohort (APC) effects during 1987–2010 were evaluated by log-likelihood estimates in Poisson regression models presented as incidence rate ratios (IRR).ResultsThere were 399,596 hip fractures in SE and 248,773 in DK. Age-standardized hip fracture rate was stable in SE men but decreased in SE women and in DK. Combined period + cohort effects were generally stronger in SE than DK and in women than men. IRR per period ranged from 1.05 to 1.30 in SE and 0.95 to 1.21 in DK. IRR per birth cohort ranged from 1.07 to 3.13 in SE and 0.77 to 1.67 in DK. Relative period effects decreased with successive period in SE and described a convex curve in DK. Relative cohort effects increased with successive birth cohort in both countries but with lower risks for DK women and men and SE women born around the 1930s (age 75–86 years today and responsible for most hip fractures) partly explaining the recent downturn. Men and women born thereafter however seem to have a higher hip fracture risk, and we expect a reversal of the present decline in rates, with increasing hip fracture rates in both Denmark and Sweden during the upcoming decade.ConclusionsTime trends, cohort, and period effects were different in SE and DK. This may reflect differences in general health as evident in known differences in life expectancy, healthcare organization, and prevention such as use of anti-osteoporosis drugs. Analyses indicate that hip fracture rates may increase in the not so far future.Electronic supplementary materialThe online version of this article (doi:10.1007/s00198-016-3768-3) contains supplementary material, which is available to authorized users.

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