236 The role of somatostatin and octreotide in preventing the post endoscopic increase of HVPG in cirrhotics with bleeding varices

Predicting failure to control bleeding and mortality in acute variceal bleeding

“…Interestingly there was a sustained rise of portal pressure after sclerotherapy, but not after band ligation. In addition, Vlachogiannakos et al [17] showed that somatostatin but not octreotide effectively prevents the post-endoscopic increase of HVPG. With the prognostic association of high HVPG with the course of bleeding (using vasoactive drugs and endoscopic therapy) and mortality, a randomized study showed that urgent TIPS in patients with HVPG >20 mmHg protected against continued or repeated bleeding and reduced mortality [15].…”