Geometric Factors Affecting the Displacement Forces in an Aortic Endograft With Crossed Limbs: A Computational Study

Abstract

Apart from minor differentiations due to geometric alterations, the customary bifurcated and crossed-limbs endografts present similar hemodynamic performance. Further clinical studies should be conducted to confirm the clinical applicability of these findings.

The shear stess profile of the pivotal fenestrated endograft at the level of the renal branches: A computational study for complex aortic aneurysms

“…The mesh size chosen was the same as the one used in another study, where a mesh independence study was successfully performed. 15…”

“…7 Our estimations were based on computational AAA models and fluid-structure-interaction (FSI) simulations, which have been described and used extensively in the past for assessment of the factors determining the hemodynamic behavior of endovascularly-treated AAAs. [10][11][12][13][14][15] Materials and methods An EG model which included two iliac members and two renal branches (i.e. SGs) was computationally constructed based on typical EG dimensions.…”

“…The mesh size chosen was the same as the one used in another study, where a mesh independence study was successfully performed. 15 No-slip boundary conditions were chosen for the EG wall, while the flow and pressure waveforms during a period of 1 s, as previously reported by Figueroa et al, were used as velocity inlet and pressure outlet boundary conditions (Figure 3a-c) at iliac and renal sites. 3,13 The resultant waveforms were discretized in time with 50 equal time-steps.…”

Applying Findings of Computational Studies in Vascular Clinical Practice: Fact, Fiction, or Misunderstanding?

“…[16][17][18] Indeed, it seems difficult to compare the hemodynamic or clinical performance of different types of endografts between several patient groups, since certain patient-specific factors, e.g., the configuration of the iliac vessels and the level of peripheral occlusive disease, may confound the effect of the endograft's structural differences on limb patency and incidence of migration and endoleaks. [19][20][21][22] Consequently, under this perspective, subtle geometrical models of unusual or complex endograft patterns, such as the cross-limbs configuration [19][20][21] and fenestrated 22 designs, respectively, can be computationally examined, preceding or even inspiring large-scale clinical studies on the same issue. More intriguingly, as modeling techniques evolve, finite element analysis can be performed for direct comparisons of the mechanical stresses and strains acting on a number of commerciallyavailable device components under a variety of angulations, depicting potential advantages or drawbacks between them.…”

Computational modelling: moonlighting on the neuroscience and medicine

“…Computational models have been used to improve the design of implanted devices including the coronary artery stents, artificial heart valves, the mechanics of blood vessel growth, blood flow, and heart valves (57). The models are also promising for further study of obesity therapy (58).…”