Abstract:Objectives: 'Mental defeat' (MD) has been identified amongst people with chronic pain as a type of 'self-processing' related to social role and rank. Research has linked it to anxiety, pain interference and functional disability. The relationship between MD and other cognitive constructs, such as hopelessness and depression remains poorly understood. The present study considers the association between MD, pain symptomatology and self-efficacy in the context of other cognitive factors. Methods: Fifty-nine participants completed a questionnaire pack assessing anxiety, depression, hopelessness, pain catastrophizing, and mental defeat in order to examine the relationship with pain symptomatology and selfefficacy. Results: Linear multiple regression analyses showed that anxiety was most strongly associated with pain symptomatology, accounting for 26% of the variance, while catastrophizing showed the strongest association with sensory pain, and mental defeat the strongest association with affective pain. Finally, mental defeat was found to be strongly associated with painrelated self-efficacy, accounting for 47% of the variance. Conclusion: This research has demonstrated the potential importance of assessing mental defeat in chronic pain patients suggesting that targeting these cognitions during interventions and therapy could be valuable. This may have an impact on how well people feel cope with their pain. Further, the study indicates that mental defeat differs from related cognitive constructs involved in pain, such as depression, hopelessness and catastrophizing.https://mc.manuscriptcentral.com/bjpain British Journal of Pain 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 poorly understood. The present study considers the association between MD, pain 7 symptomatology and self-efficacy in the context of other cognitive factors. 8Methods: Fifty-nine participants completed a questionnaire pack assessing anxiety, 9 depression, hopelessness, pain catastrophising, and mental defeat in order to 10 examine the relationship with pain symptomatology and self-efficacy. 11