Survival following spinal cord infarction

New, Peter W; McFarlane, Caroline

doi:10.1038/sc.2013.14

Cited by 11 publications

(20 citation statements)

References 15 publications

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“…Among those studies that investigated the causes of death, the reported leading causes of death were diverse (n = 22) [9,10,19,37,40,42,51,65,74,78,84,86,87,88,89,90,92,94,97,106,107,108,109]. The most commonly reported leading cause of death was pneumonia (n = 5) [19,51,78,94,109], followed by heart disease (n = 3) [10,74,84].…”

Section: Resultsmentioning

confidence: 99%

“…The most commonly reported leading cause of death was pneumonia (n = 5) [19,51,78,94,109], followed by heart disease (n = 3) [10,74,84]. Only one study reported the crude number of deaths for causes of mortality by gender, and found that the leading cause of death among males was heart disease, compared to an equal number of deaths due to digestive disorders as well as heart disease for females [84].…”

Section: Resultsmentioning

confidence: 99%

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Mortality and Longevity after a Spinal Cord Injury: Systematic Review and Meta-Analysis

Chamberlain

Meier²,

Mader³

et al. 2015

Neuroepidemiology

135

101

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Background/Aims: Mortality and longevity studies of spinal cord injury (SCI) are essential for informing healthcare systems and policies. This review evaluates the current evidence among people with SCIs worldwide in relation to the WHO region and country income level; demographic and lesion characteristics; and in comparison with the general population. Methods: A systematic review of relevant databases for original studies. Pooled estimates were derived using random effects meta-analysis, restricted to traumatic SCI. Results: Seventy-four studies were included. In-hospital mortality varied, with pooled estimates of 24.1% (95% confidence interval (CI) 14.1-38.0), 7.6% (95% CI 6.3-9.0), 7.0% (95% CI 1.5-27.4), and 2.1% (95% CI 0.9-5.0) in the WHO regions of Africa, the Americas, Europe and Western Pacific. The combined estimate for low- and middle-income countries was nearly three times higher than for high-income countries. Pooled estimates of first-year survival were 86.5% (95% CI 75.3-93.1), 95.6% (95% CI 81.0-99.1), and 94.0% (95% CI 93.3-94.6) in the Americas, Europe and Western Pacific. Pooled estimates of standardized mortality ratios in tetraplegics were 2.53 (2.00-3.21) and 2.07 (1.47-2.92) in paraplegics. Conclusion: This study found substantial variation in mortality and longevity within the SCI population, compared to the general population, and between WHO regions and country income level. Improved standardization and quality of reporting is needed to improve inferences regarding the extent to which mortality outcomes following an SCI are related to healthcare systems, services and policies.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Mortality and Longevity after a Spinal Cord Injury: Systematic Review and Meta-Analysis

Chamberlain

Meier²,

Mader³

et al. 2015

Neuroepidemiology

135

101

View full text Add to dashboard Cite

show abstract

“…SCI in the setting of cardiac arrest and acute aortic rupture or dissection, and those with high cervical lesions are at greatest risk for fatality [5]. Patients with SCI have a persistently elevated mortality rate after hospital discharge [5,6,11,18,20,21]. In the largest study of 115 patients with SCI, 5-and 10-year survival rates were 55% and 42%, respectively [5].…”

Section: Clinical Presentation Etiology and Prognosismentioning

confidence: 98%

“…The acute fatality rate varies depending on the case mix in the retrospective analysis of patients [16][17][18][19][20]. SCI in the setting of cardiac arrest and acute aortic rupture or dissection, and those with high cervical lesions are at greatest risk for fatality [5].…”

Section: Clinical Presentation Etiology and Prognosismentioning

confidence: 99%

Current and emerging treatment options for spinal cord ischemia

Nardone

Pikija

Mutzenbach

et al. 2016

Drug Discovery Today

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“…Aortic disease is the most common cause, most probably due to vulnerability of the thoraco-lumbar spinal cord to hypoperfusion [1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Other aetiologies include atherosclerosis, adjacent spinal degenerative disease, fibrocartilaginous embolism (FCE), vertebral dissection, systemic hypotension, cardiac embolism, coagulopathies, vasculitides, surfing-related myelopathy and decompression sickness [1][2][3][4][5][6][7][8][9][10][11][15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%