Background: Impaired right ventricular (RV) function markedly impacts the prognosis in patients (pts) with functional mitral regurgitation (FMR). In such pts, significant recovery of RV function after MitraClip (MC) therapy has been shown. We sought to identify echocardiographic and/or hemodynamic variables predicting recovery of RV function after MC therapy. Methods: Of 194 pts with significant FMR receiving MC therapy at our institution, impaired RV function (defined as tricuspid annular plane systolic excursion [TAPSE] < 18mm) was present at baseline in 78 (40%). Six-week echocardiographic follow-up was obtained from 36 pts (71 AE 11 years; 23 men [64%]). Results: Recovery of RV functiondefined as a change in TAPSE (DTAPSE) >3mmwas observed at 6 weeks in 8/36 pts (22%). These 8 pts (mean DTAPSE 5.6 AE 0.9mm) differed from the 28 pts with DTAPSE 3mm (mean DTAPSE