“…154,155,156 The pH of self-etch and self-adhesive materials directly relates to their reduced potential, as compared to that of phosphoric acid, 157,158 to etch the highly-mineralized enamel. 25,155,156,157,159,160,161,162,163,164 Hence, increasing its surface area and creating deep etch-pits remains important for the achievement of an effective and durable bond to enamel. 4,165,166,167,168 According to the buffering capacity that such substrate offers to the action of self-etch systems in general, it can be expected that they do have a lower demineralizing effect on the hydroxyapatite-rich enamel, which ultimately compromise their bonding effectiveness.…”