Combined non-invasive functional and anatomical diagnostic work-up in clinical practice: the magnetic resonance and computed tomography in suspected coronary artery disease (MARCC) study

Abstract

The combined use of CTCA and CMR significantly improved specificity and overall diagnostic accuracy for the detection of significant CAD and allowed the detection of alternative (extra-)cardiac disease in patients without significant CAD.

2014 Korean Guidelines for Appropriate Utilization of Cardiovascular Magnetic Resonance Imaging: A Joint Report of the Korean Society of Cardiology and the Korean Society of Radiology

“…Stress CMR perfusion imaging can detect functionally significant CAD defined as FFR <0.75 with excellent sensitivity (91%), specificity (94%), and positive and negative predictive values (91% and 94%, respectively). In a recent study by Groothuis et al, ( 64 ). the addition of stress CMR perfusion imaging to CT coronary angiography significantly improved specificity and overall diagnostic accuracy for the detection of significant CAD as defined by catheter-based XCA with conditional FFR measurement.…”

2014 Korean Guidelines for Appropriate Utilization of Cardiovascular Magnetic Resonance Imaging: A Joint Report of the Korean Society of Cardiology and the Korean Society of Radiology

“…Stress CMR perfusion imaging can detect functionally significant CAD defined as FFR <0.75 with excellent sensitivity (91%), specificity (94%), and positive and negative predictive values (91% and 94%, respectively). In a recent study by Groothuis et al, 64) the addition of stress CMR perfusion imaging to CT coronary angiography significantly improved specificity and overall diagnostic accuracy for the detection of significant CAD as defined by catheter-based XCA with conditional FFR measurement. Thus, in clinical practice, stress CMR can subsequently be used to assess the hemodynamic significance of CAD and to direct revascularization.…”

Cardiac magnetic resonance imaging derived quantification of myocardial ischemia and scar improves risk stratification and patient management in stable coronary artery disease

“…Cardiac magnetic resonance imaging (CMR) is an established non-invasive method for the diagnosis of CAD [9]. It offers several advantages in comparison to other imaging techniques, such as a high spatial and temporal resolution, clear image contrast and lack of ionizing radiation [10,11]. It is viable to reliably detect and visualize myocardial ischemia as well as necrotic tissue in one single exam [11].…”

“…It offers several advantages in comparison to other imaging techniques, such as a high spatial and temporal resolution, clear image contrast and lack of ionizing radiation [10,11]. It is viable to reliably detect and visualize myocardial ischemia as well as necrotic tissue in one single exam [11]. It has been shown to provide important prognostic information in patients with known or suspected CAD [12][13][14][15][16][17][18][19].…”