Results of a cosmetovigilance survey in The Netherlands

Salverda, Joanne G. W.; Bragt, Peter J. C.; Wit-Bos, Lianne de; Rustemeyer, Thomas; Coenraads, Pieter Jan; Tupker, Ron A.; Kunkeler, L.; Boer, Anna-Marijke Laheij-de; Stenveld, Harma J.; Ginkel, Cees J. W. van; Kooi, Myrna W.; Bourgeois, Francois C.; Gorcum, Teetske F. van; Engelen, J.G.M. van; Dijk, Remmelt van; Graaf, Judith de; Donker, G.A.; Heer, Cees de; Bruynzeel, Derk P.

doi:10.1111/cod.12005

Cited by 45 publications

(42 citation statements)

References 35 publications

(53 reference statements)

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“…The same applies for skin allergies, where the rate of deterioration has accelerated in the past 5-10 years [9][10][11][12][13][14][15][16][17], leading to some labelling it a 'skin allergy epidemic'. Multiple environmental factors are suggested to be contributing, but it has been increasingly linked to synthetic additives in cosmetics [18][19][20][21][22][23]. The exposure of normal, western skin to twenty-first-century cosmetics, soap, antibiotics, steroids and showering/washing [24], does appear to have altered the natural microbiota environment of humans, especially in the developed 2 of 21 world [11,[25][26][27][28][29][30][31].…”

Section: The Skin Allergy Epidemicmentioning

confidence: 99%

The Role of Every-Day Cosmetics in Altering the Skin Microbiome: A Study Using Biodiversity

Wallen-Russell¹

2018

Preprint

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As described in previous work, the use of synthetic chemical ingredients in modern cosmetics is postulated to be a cause of damage to the skin microbiome. The discovery that biodiversity on the human skin is currently the only reliable indicator of skin health, meant that for the first time, a mechanism to test for healthy skin was possible. Using this mechanism and in collaboration with The Medical University of Graz, who carried out the independent study, this work aimed to help answer whether modern day synthetic cosmetics are a main cause of long term damage to the skin microbiome. Thirty-two human participants tested three different face washes for their effect on the skin’s microbial diversity, along with skin pH, moisture and TEWL (trans-epidermal water loss), washing twice a day for four weeks. The upper volar forearm of the volunteers was swabbed at the beginning, two weeks in and end (four weeks). 16S rRNA sequencing was used. One leading ‘natural’ brand full of synthetic ingredients, a leading synthetic brand and a 100% natural face wash were used. Results give the first indications of a link between synthetic ingredients in a cosmetics product, and its effect on skin microbiome biodiversity. It paves the way for future studies on the topic with a larger sample group, longer test period and standardised methodology to create a universal standard for testing the health of skin using benchmark diversity values. This can be used in the future to test the effectiveness of cosmetics or ingredients on skin health, leading to the banning of products proven to harm the skin’s natural environment.

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Section: The Skin Allergy Epidemicmentioning

confidence: 99%

The Role of Every-Day Cosmetics in Altering the Skin Microbiome: A Study Using Biodiversity

Wallen-Russell¹

2018

Preprint

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show abstract

“…An increasing number of studies have linked these health issues to synthetic additives in cosmetics [100][101][102][103][104][105]. The exposure of normal, western skin to twenty-first-century cosmetics, soap, antibiotics, steroids and showering, does appear to have altered the natural microbiota environment of humans, especially in the developed world [14,16].…”

Section: Are Cosmetics a Major Contributor To The Skin Allergy Epidemic?mentioning

confidence: 99%

Meta Analysis of Skin Microbiome: New Link between Skin Microbiota Diversity and Skin Health with Proposal to Use This as a Future Mechanism to Determine Whether Cosmetic Products Damage the Skin

Wallen-Russell

Wallen-Russell²

2017

Cosmetics

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Abstract:There is a skin allergy epidemic in the western world, and the rate of deterioration has increased significantly in the past 5-10 years. It is probable that there are many environmental contributing factors, yet some studies have linked it primarily to the rise in the use of synthetic chemical ingredients in modern cosmetics. Our challenge, therefore, was to find a mechanism to determine the effect these substances have on skin health, and whether they really are a primary cause of long term damage to the skin. The first problem is the lack of any definitive way to measure skin health. Motivated by the overwhelming evidence for a link between deficient gut flora and ill health, we decided to look at whether our skin microbiota could similarly be used as an indicator of skin health. Our research illustrates how microbiota diversity alone can predict whether skin is healthy or not, after we revealed a complete lack of conclusive findings linking the presence or abundance of particular species of microbe to skin problems. This phenomenon is replicated throughout nature, where high biodiversity always leads to healthy ecosystems. 'Caveman' skin, untouched by modern civilisation, was far different to "western" skin and displayed unprecedented levels of bacterial diversity. The less exposed communities were to western practices, the higher the skin diversity, which is clear evidence of an environmental factor in the developed world damaging skin. For the first time we propose benchmark values of diversity against which we can measure skin to determine how healthy it is. This gives us the ability to be able to predict which people are more likely to be prone to skin ailments, and start to test whether cosmetic ingredients and products are a main cause of the skin allergy epidemic.Keywords: biodiversity; skin allergy; benchmark skin health values; effect of synthetic cosmetics on skin; 21st century skin ailments; measure skin health; healthy skin ecosystem; healthy skin bacteria; damaged skin bacteria; perfect skin

show abstract

“…An increasing number of studies have linked these health issues to synthetic additives in cosmetics (99)(100)(101)(102)(103)(104) . The exposure of normal, western skin to twenty-first-century cosmetics, soap, antibiotics, steroids and showering, does appear to have altered the natural microbiota environment of humans, especially in the developed world (14,16) .…”

Section: Are Cosmetics a Major Contributor To The Skin Allergy Epidemic?mentioning

confidence: 99%

New Link between Skin Microbiota Diversity and Skin Health: Proposal to Use This as a Mechanism to Determine Whether Cosmetic Products Damage the Skin and Are a Cause of the Skin Allergy Epidemic

Wallen-Russell¹,

Wallen-Russell²

2017

Preprint

View full text Add to dashboard Cite

There is a skin allergy epidemic in the western world, and the rate of deterioration has increased significantly in the past 5-10 years. It is probable that there are many environmental contributing factors, yet some studies have linked it primarily to the rise in the use of synthetic chemical ingredients in modern cosmetics. Our challenge, therefore, was to find a mechanism to determine the effect these substances have on skin health, and whether they really are a primary cause of long term damage to the skin. The first problem is the lack of any definitive way to measure skin health. Motivated by the overwhelming evidence for a link between deficient gut flora and ill health, we decided to look at whether our skin microbiota could similarly be used as an indicator of skin health. Our research illustrates how it is microbiota diversity alone that can predict whether skin is healthy or not, after we revealed a complete lack of conclusive findings linking the presence or abundance of particular species of microbe to skin problems. This phenomenon is replicated throughout nature, where high biodiversity always leads to healthy ecosystems. 'Caveman' skin, untouched by modern civilisation, was far different to 'western' skin and displayed unprecedented levels of bacterial diversity. The less exposed communities were to western practices, the higher the skin diversity, which is clear evidence of an environmental factor in the developed world damaging skin. For the first time we propose benchmark values of diversity against which we can measure skin to determine how healthy it is. This gives us the ability to be able to predict which people are more likely to be prone to skin ailments, and start to test whether cosmetic ingredients and products are a main cause of the skin allergy epidemic.Keywords: biodiversity; skin allergy; benchmark skin health values; effect of synthetic cosmetics on skin; 21 st century skin ailments; measure skin health; healthy skin ecosystem; healthy skin bacteria; damaged skin bacteria; perfect skin

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Results of a cosmetovigilance survey in The Netherlands

Abstract: Further investigations are recommended on the prevalence of isothiazolinone-induced allergic contact dermatitis and the allergenic potential of co-polymers/cross-polymers.

Cited by 45 publications

References 35 publications

The Role of Every-Day Cosmetics in Altering the Skin Microbiome: A Study Using Biodiversity

The Role of Every-Day Cosmetics in Altering the Skin Microbiome: A Study Using Biodiversity

Meta Analysis of Skin Microbiome: New Link between Skin Microbiota Diversity and Skin Health with Proposal to Use This as a Future Mechanism to Determine Whether Cosmetic Products Damage the Skin

New Link between Skin Microbiota Diversity and Skin Health: Proposal to Use This as a Mechanism to Determine Whether Cosmetic Products Damage the Skin and Are a Cause of the Skin Allergy Epidemic

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