Videofluoroscopic‐guided botulinum toxin injections for pharyngoesophageal spasm after total laryngectomy

‘Endoflip® evaluation of pharyngo‐oesophageal segment tone and swallowing in a clinical population: a total laryngectomy case series’

“…Altered pharyngo‐oesophageal segment tone can lead to impaired pharyngeal bolus clearance during swallowing and to regurgitation of oesophageal contents back into the pharynx post swallow. Pharyngo‐oesophageal spasm can also impact markedly on successful voice production post total laryngectomy which can have considerable effects on quality of life . Interventions commonly employed to optimise pharyngo‐oesophageal segment tone, and hence, voice and swallowing post total laryngectomy include endoscopic dilation procedures, myotomy, pharyngeal neurectomy and botulinum toxin injections to the cricopharyngeus (CP) muscle within the pharyngo‐oesophageal segment .…”

“…Pharyngo‐oesophageal spasm can also impact markedly on successful voice production post total laryngectomy which can have considerable effects on quality of life . Interventions commonly employed to optimise pharyngo‐oesophageal segment tone, and hence, voice and swallowing post total laryngectomy include endoscopic dilation procedures, myotomy, pharyngeal neurectomy and botulinum toxin injections to the cricopharyngeus (CP) muscle within the pharyngo‐oesophageal segment . However, candidacy for and effectiveness of these interventions can be quite subjective based on unreliable measures obtained from videofluoroscopy and manometry examinations (Fig.…”

Lateral Transcervical In‐office Botulinum Toxin Injection for Retrograde Cricopharyngeal Dysfunction

“…Should the current modification to the described technique be ineffective, further modifications or adjuncts such as fluoroscopy-guided injections might also be considered in the future. 8,9 The most common side effect following the injections was dysphagia, with an average incidence of 56%. In our cohort, 66% of the patients who underwent injection in the OR and 46% of IO had dysphagia.…”

Treatment of Gastrointestinal Sphincters Spasms with Botulinum Toxin A

“…BT has also been used in a variety of less well characterized esophageal conditions including diffuse esophageal spasm (DES) and patients with non-cardiac chest pain suspected to be on the basis of a dysfunctional esophagus. DES is a condition that is related to achalasia and may be associated with LES dysfunction as well [ 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 ]. The largest clinical trial assessing the effect of BT in DES patients evaluated 9 patients [ 97 , 98 ].…”