Chondrosarcoma of the Subglottic Larynx

Jackson, Ryan; Leon, Marino E.; McCaffrey, Thomas V.

doi:10.1002/lary.23957

Cited by 11 publications

(10 citation statements)

References 16 publications

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“…1,2 Chondrosarcoma typically occurs in patients between the fifth and sixth decades, and the incidence is 3 times higher in males than in females. [3][4][5][6][7][8][9] The exact etiopathogenesis of chondrosarcoma in the thyroid cartilage remains unclear. 10 Disordered ossification is most often described as the possible etiology.…”

Section: Discussionmentioning

confidence: 99%

“…[15][16][17] Diagnosis of chondrosarcomas can be challenging given the slow rate of growth and nonspecific symptoms at presentation, such as hoarseness, dyspnea, airway obstruction, dysphagia, and painless neck mass. [3][4][5][6][7][8][9] The fundamental diagnostic step is endoscopic examination of the larynx and imaging. Smooth asymmetry of the supraglottic area should arouse suspicion of laryngocele, chondroma, chondrosarcoma, and other less frequent pathologies.…”

Section: Discussionmentioning

confidence: 99%

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Chondrosarcoma of the Thyroid Cartilage Successfully Treated With Partial Resection of the Thyroid Cartilage

et al. 2021

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Chondrosarcoma of the thyroid cartilage is a sporadic disease with nonspecific clinical presentation. Smooth swelling of the supraglottic area should arouse suspicion of possible pathology. In addition to laryngoceles, which usually do not have a significant impact, otolaryngologists should consider chondrosarcoma of the thyroid cartilage and indicate computed tomography (CT). Late diagnosis leads to worse prognosis, particularly worse voice after more extensive surgery, need for tracheostomy, and worse survival from higher degree chondrosarcomas.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Chondrosarcoma of the Thyroid Cartilage Successfully Treated With Partial Resection of the Thyroid Cartilage

et al. 2021

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“…Laryngeal chondrosarcoma is a rare, slow-growing malignant tumor of the larynx 1 . Clinical symptoms and signs of the disease such as dyspnea, stridor, hoarseness or dysphagia may indicate the localization and size of the tumor, and may indicate the potential difficulties in airway management 5,8 .…”

Section: Discussionmentioning

confidence: 99%

“…Chondrosarcoma is a rare mesenchymal tumor accounting for approximately 0.1% of all head and neck malignancies 1,2 . The most common location of chondrosarcoma within the larynx is cricoid cartilage, thyroid and arytenoid cartilage 3 .…”

Section: Introductionmentioning

confidence: 99%

Laryngeal Chondrosarcoma: Successful Use of Video Laryngoscope in Anticipated Difficult Airway Management

2016

ACC

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SUMMARY -Laryngeal chondrosarcoma is a rare mesenchymal tumor, most frequently affecting cricoid cartilage. The objective of this report is to present successful video laryngoscope usage in a patient with anticipated difficult airway who refused awake fiberoptic endotracheal intubation (AFOI). A 59-year-old male patient was admitted in our hospital due to difficulty breathing and swallowing. On clinical examination performed by ENT surgeon, preoperative endoscopic airway examination (PEAE) could not be performed properly due to the patient's uncooperativeness. Computed tomography revealed a spherical tumor that obstructed the subglottic area almost entirely. Due to the narrowed airway, the first choice for the anticipated difficult airway management was AFOI, which the patient refused. Consequently, we decided to perform endotracheal intubation with indirect laryngoscope using a C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany). Reinforced endotracheal tube (6.0 mm internal diameter) was placed gently between the tumor mass and the posterior wall of the trachea in the first attempt. Confirmation of endotracheal intubation was done by capnography. In a patient with subglottic area chondrosarcoma refusing PEAE and AFOI, video laryngoscope is a particularly helpful device for difficult airway management when difficult airway is anticipated.

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“…of casesPeriodAuthorsYearRemarksUniversity Hospital Heidelberg, Germany72013–2018Akbaba et al [44]2018These cases were treated upfront with raster-scanned carbon ion RadiotherapyJohns Hopkins, School of Medicine, Baltimore, USA62004–2013Karatayli-Ozgursoy et al [45]2016All were of cricoid origin, three out of six had a recurrenceGuy’s and St Thomas’ NHS Foundation Trust, London, UK51996–2012Stavrakas et al [46]2016Dept. of ORL, Turin, Rome, Belluno, Italy62006–2013Damiani et al [47]2014All had conservative surgical approachCentro Hospitalar e Universitário de Coimbra, Portugal62002–2012Oliveira et al [48]2014One had high grade, five underwent total laryngectomyMontpellier University Hospital, France72001–2008Pelliccia et al [49]2014All had low-grade cricoid chondrosarcomaUniversity of Brescia, Italy162001–2013Piazza et al [41]2014Eleven were of low grade and five of intermediate gradeMoffitt Cancer Institute USA52004–2011Jackson et al [50]2013Four were of low grade and one of intermediate gradeTel Aviv University, Israel61959–2010Buda et al [51]2012Recurrence developed in two patients 2 and 8 years after primary treatmentHarvard Medical School USA…”

Section: Chondrosarcomamentioning

confidence: 99%

Differing characteristics of cartilaginous lesions of the larynx

Ferlito¹,

Devaney

Mäkitie

2019

Eur Arch Otorhinolaryngol

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IntroductionThe tissues of the laryngeal region only rarely harbor primary cartilaginous lesions, and squamous cell carcinoma remains the most frequently encountered malignant tumor in this area.Materials and MethodsWe reviewed the salient histological features of cartilaginous laryngeal lesions to provide differential diagnostics and guidelines for distinguishing the benign from the malignant ones.ResultsCartilaginous neoplasms of the larynx include chondroma and chondrosarcoma. Among the overarching group of all forms of laryngeal sarcoma, chondrosarcoma forms the most common entity in the larynx, followed by rhabdomyosarcoma. Cartilaginous tumors comprise about 0.1%–1% of all laryngeal neoplasms with chondrosarcomas being more frequently encountered than chondromas. Several neoplasms earlier reported as giant-cell tumors of the larynx would most likely, using current terminology, be classified as cases of undifferentiated pleomorphic sarcoma (previously known as malignant fibrous histiocytoma, giant-cell variant) or aneurysmal bone cyst.ConclusionWhen true laryngeal sarcomas do exist, they may prove to be challenging lesions both for the pathologist and the treating clinician. The diagnostic problems are mainly a result of the infrequent exposure of clinicians and diagnosticians to these lesions.

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Chondrosarcoma of the Subglottic Larynx

Abstract: 4.

Cited by 11 publications

References 16 publications

Chondrosarcoma of the Thyroid Cartilage Successfully Treated With Partial Resection of the Thyroid Cartilage

Chondrosarcoma of the Thyroid Cartilage Successfully Treated With Partial Resection of the Thyroid Cartilage

Laryngeal Chondrosarcoma: Successful Use of Video Laryngoscope in Anticipated Difficult Airway Management

Differing characteristics of cartilaginous lesions of the larynx

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