Catheter ablation of atrial fibrillation guided by a 3D electroanatomical mapping system: a 2-year follow-up study from the Italian Registry On NavX Atrial Fibrillation ablation procedures (IRON-AF)

Forleo, Giovanni B.; Martino, Giuseppe; Mantica, Massimo; Menardi, Endrj; Trevisi, Nicola; Faustino, Massimiliano; Muto, Carmine; Perna, Francesco; Santamaria, Matteo; Pandozi, Claudio; Pappalardo, Augusto; Mancusi, Carmine; Romano, Enrico; Bella, Paolo Della; Tondo, Claudio

doi:10.1007/s10840-012-9772-4

Cited by 3 publications

(2 citation statements)

References 26 publications

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“…Nevertheless, a "real life" registry, focusing on a general, unselected population, holds the potential to describe tendencies among categories/groups or even Countries that have not emerged yet. The utility of a National survey stems from the fact that many recent studies may not be representative of the national territory, as they focus on a singular ablation technique or on patients with a certain geographical origin, implying differences in environmental risk factors, genetic predisposition and comorbidities [13][14][15][16]. Moreover, data derived from clinical studies may relate to adoption of specific strategies in AF management and/or indication to catheter ablation.…”

Section: Discussionmentioning

confidence: 99%

Atrial fibrillation ablation long-term ESC-EHRA EORP AFA LT registry: in-hospital and 1-year follow-up findings in Italy

Anselmino

Ballatore

Saglietto

et al. 2020

Journal of Cardiovascular Medicine

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Aim: To report the Italian data deriving from the ESC-EORP Atrial Fibrillation Ablation Long-Term (AFA LT) registry.Methods and results: Ten Italian centers enrolled up to 50 consecutive patients undergoing AF ablation. Of 318 patients included 5 (1.6%) did not undergo catheter ablation, 1 had ablation partially done and 62 were lost at 1-year follow-up. Women were less represented (23.6%) and the median age was 60.0 years. 195 patients (62.3%) suffered paroxysmal AF, whereas only 9 (2.9%) had long-standing persistent AF. Most Italian patients (92.3%) were symptomatic but suffering less symptomatic events than patients enrolled in other countries (median of 2 events in the month preceding the ablation vs. 3, respectively; p<0.0001). The main finding of the study is that the success rate at 1-year, with and without antiarrhythmic drugs, was 76.4%, consistent with other participating countries (73.4%). This result was obtained however with a significantly lower prevalence of 1-year adverse events (7.3% vs. 16.6%, p<0.0001). Procedure duration and fluoroscopy total time resulted shorter in Italy (145 vs. 160, p=0.0005, and 16.9 vs. 20.0 minutes, p=0.0018, respectively); however, radiation dose per body surface area was greater (37.5 vs. 26.0 mGy/cm2, p=0.0022). Conclusion:The demographic characteristics of patients undergoing AF ablation are similar to those reported in other countries. The success rate in Italy is consistent with other countries, whereas the complications rate is lower.

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Section: Discussionmentioning

confidence: 99%

Atrial fibrillation ablation long-term ESC-EHRA EORP AFA LT registry: in-hospital and 1-year follow-up findings in Italy

Anselmino

Ballatore

Saglietto

et al. 2020

Journal of Cardiovascular Medicine

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“…In the IRON-AF registry, 545 consecutive patients (age 60.4 ± 9.8, 67% male) referred for AF ablation guided by the NavX system (St. Jude Medical Inc., St. Paul, MN, USA) were prospectively enrolled [1]. Ablation strategies were all aimed at isolation or encircling all accessible pulmonary veins with radiofrequency energy.…”

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confidence: 99%

Clinical impact of catheter ablation in patients with asymptomatic atrial fibrillation: The IRON-AF (Italian Registry on NavX Atrial Fibrillation Ablation Procedures) study

Forleo

Martino

Mantica

et al. 2013

International Journal of Cardiology

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Atrial fibrillation: to map or not to map?

et al. 2013

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Isolation of the pulmonary veins may be an effective treatment modality for eliminating atrial fibrillation (AF) episodes but unfortunately not for all patients. When ablative therapy fails, it is assumed that AF has progressed from a trigger-driven to a substrate-mediated arrhythmia. The effect of radiofrequency ablation on persistent AF can be attributed to various mechanisms, including elimination of the trigger, modification of the arrhythmogenic substrate, interruption of crucial pathways of conduction, atrial debulking, or atrial denervation. This review discusses the possible effects of pulmonary vein isolation on the fibrillatory process and the necessity of cardiac mapping in order to comprehend the mechanisms of AF in the individual patient and to select the optimal treatment modality.

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Catheter ablation of atrial fibrillation guided by a 3D electroanatomical mapping system: a 2-year follow-up study from the Italian Registry On NavX Atrial Fibrillation ablation procedures (IRON-AF)

Abstract: This prospective, multicenter clinical experience provides significant insights into current ablation care of patients with AF. Despite favorable outcomes, real-world complication rates appear higher than previously recognized.

Cited by 3 publications

References 26 publications

Atrial fibrillation ablation long-term ESC-EHRA EORP AFA LT registry: in-hospital and 1-year follow-up findings in Italy

Atrial fibrillation ablation long-term ESC-EHRA EORP AFA LT registry: in-hospital and 1-year follow-up findings in Italy

Clinical impact of catheter ablation in patients with asymptomatic atrial fibrillation: The IRON-AF (Italian Registry on NavX Atrial Fibrillation Ablation Procedures) study

Atrial fibrillation: to map or not to map?

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