Regulation of brain activity in the fusiform face and parahippocampal place areas in 7–11-year-old children

Vuontela, Virve; Jiang, Ping; Tokariev, Maksym; Savolainen, Petri; Ma, Yuanye; Aronen, Eeva T.; Fontell, Tuija; Liiri, Tiina; Ahlström, Matti; Salonen, Oili; Carlson, Synnöve

doi:10.1016/j.bandc.2012.11.003

Cited by 15 publications

(26 citation statements)

References 80 publications

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“…The child participants were the same as those in the study of Vuontela et al (2013), in which more details regarding participant demographics were described. Two new adults were included in the present study.…”

Section: Participantsmentioning

confidence: 99%

“…The task performed during scanning was a visual 1-back WM task (Vuontela et al, 2013). N-back tasks have been widely used earlier and proven suitable for investigating cognitive processes in school-aged children (Casey et al, 1995;Nelson et al, 2000;Taylor, Donner, & Pang, 2011;Thomas et al, 1999;Vuontela et al, 2003Vuontela et al, , 2009).…”

Section: Tasks and Stimulimentioning

confidence: 99%

“…Studies of specific perceptual and cognitive functions have examined response patterns in functionally defined category-selective regions in the visual cortex that respond preferentially to objects, faces or scenes (Epstein & Kanwisher, 1998;Kanwisher, McDermott, & Chun, 1997: Malach et al, 1995. Several studies have shown a prolonged maturation for the face-selective cortex (Golarai, Liberman, Yoon, & Grill-Spector, 2010;Golarai et al, 2007;Scherf, Behrmann, Humphreys, & Luna, 2007;Scherf, Luna, Avidan, & Behrmann, 2011) and the emerging face processing network (Cohen Kadosh, Cohen Kadosh, Dick, & Johnson, 2011), and weaker top-down regulation of activity of the fusiform face area (FFA) in children compared to adults (Vuontela et al, 2013). In contrast, less is known about the functional maturation and cognitive control of the place-selective cortex and associated functional networks that support scene-specific perceptual and cognitive processing.…”

Section: Introductionmentioning

confidence: 99%

“…In our previous study (Vuontela et al, 2013), we used functional magnetic resonance imaging (fMRI) and tasks that required attention to and memorizing of scene (or face) images and suppression of face (or scene) images, respectively, to investigate the function of the PPA and the FFA in 7-11-year-old children. We found that the modulation of activation in the PPA, and FC between the PPA and the PFC, were comparable between 7-11-year-old children and young adults.…”

Section: Introductionmentioning

confidence: 99%

“…We found that the modulation of activation in the PPA, and FC between the PPA and the PFC, were comparable between 7-11-year-old children and young adults. In the present study, we analyzed further the fMRI data described in our previous study (Vuontela et al, 2013) to investigate the functional maturation of the scene-selective brain region RSC and associated functional networks, and compared the responsiveness of the RSC with that of the PPA. Based on the notion that the RSC, compared to PPA, is involved in more complex scene processing (Epstein, 2008) we hypothesized that the tasks that required selective attention to and memorizing of scene images, might also engage the RSC, but to a lesser extent than the PPA.…”

Section: Introductionmentioning

confidence: 99%

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Responsiveness and functional connectivity of the scene-sensitive retrosplenial complex in 7–11-year-old children

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et al. 2014

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Section: Participantsmentioning

confidence: 99%

Section: Tasks and Stimulimentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Responsiveness and functional connectivity of the scene-sensitive retrosplenial complex in 7–11-year-old children

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et al. 2014

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Compensatory increase of functional connectivity density in adolescents with internet gaming disorder

Yang

Gao

et al. 2016

Brain Imaging and Behavior

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Behavioral studies have demonstrated visual attention bias and working memory deficits in individuals with internet gaming disorder (IGD). Neuroimaging studies demonstrated that individuals with IGD presented abnormalities in brain structures and functions including resting-state functional connectivity (rsFC) disturbance. However, most previous studies investigated IGD-related rsFC alterations by using hypothesis-driven methods with priori selection of a region of interest, which cannot provide a full picture of the rsFC changes in IGD individuals. In this study, we recruited 27 male IGD adolescents and 35 demographically matched healthy controls (HCs) to investigate abnormal connective property of each voxel within whole brain of IGD adolescents using resting-state functional connectivity density (rsFCD) method, and further to evaluate the relationship between altered rsFCD and behavioral performances of visual attention and working memory. The results exhibited no significant intergroup difference in behavioral performance (visual working memory and attention). The IGD adolescents exhibited higher global/long-range rsFCD in the bilateral dorsal lateral prefrontal cortex (DLPFC) and the right inferior temporal cortex (ITC)/fusiform compared with the HCs. Although no significant correlation survived after Bonferroni correction, higher global/long-range rsFCD of the bilateral DLPFC was correlated with the Young's internet addiction test (IAT) score and/or behavioral performance in IGD adolescents using an uncorrected threshold of P < 0.05. In conclusion, IGD adolescents demonstrated increased rsFCD in the brain regions involved in working memory, spatial orientation and attention processing, which indicated that increased rsFCD may reflect a compensatory mechanism for maintaining the normal behavioral performance in IGD adolescents compared with the HCs.

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Altered working memory-related brain responses and white matter microstructure in extremely preterm-born children at school age

Tokariev

Vuontela

Lönnberg

et al. 2019

Brain and Cognition

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Preterm birth poses a risk for neurocognitive and behavioral development. Preterm children, who have not been diagnosed with neurological or cognitive deficits, enter normal schools and are expected to succeed as their term-born peers. Here we tested the hypotheses that despite an uneventful development after preterm birth, these children might exhibit subtle abnormalities in brain function and white-matter microstructure at school-age. We recruited 7.5-year-old children born extremely prematurely (< 28 weeks' gestation), and age-and gender-matched term-born controls (≥ 37 weeks' gestation). We applied fMRI during working-memory (WM) tasks, and investigated white-matter microstructure with diffusion tensor imaging. Compared with controls, preterm-born children performed WM tasks less accurately, had reduced activation in several right prefrontal areas, and weaker deactivation of right temporal lobe areas. The weaker prefrontal activation correlated with poorer WM performance. Preterm-born children had higher fractional anisotropy (FA) and lower diffusivity than controls in several white-matter areas, and in the posterior cerebellum, the higher FA associated with poorer visuospatial test scores. In controls, higher FA and lower diffusivity correlated with faster WM performance. Together these findings demonstrate weaker WM-related brain activations and altered white matter microstructure in children born extremely preterm, who had normal global cognitive ability.

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Regulation of brain activity in the fusiform face and parahippocampal place areas in 7–11-year-old children

Cited by 15 publications

References 80 publications

Responsiveness and functional connectivity of the scene-sensitive retrosplenial complex in 7–11-year-old children

Responsiveness and functional connectivity of the scene-sensitive retrosplenial complex in 7–11-year-old children

Compensatory increase of functional connectivity density in adolescents with internet gaming disorder

Altered working memory-related brain responses and white matter microstructure in extremely preterm-born children at school age

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