2013
DOI: 10.1097/dad.0b013e31826ffe6f
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Cutaneous Infiltrates of Acute Myelogenous Leukemia Simulating Inflammatory Dermatoses

Abstract: Some cases of specific cutaneous manifestations of acute myelogenous leukemia (AML) may mimic inflammatory dermatoses both clinically and histopathologically, presenting with an inconspicuous maculopapular eruption and with only sparse dermal infiltrates. The authors studied the histopathological and immunohistochemical features of 17 biopsies from 16 patients (11 men and 5 women, age range 15-85 years) presenting with minimal skin infiltrates as the first manifestation of AML or as first sign of recurrence af… Show more

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Cited by 23 publications
(17 citation statements)
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“…46 Morphologically, the malignant cells are centered in the dermis and can also extend into the subcutaneous tissue. The diagnosis can also be elusive because the infiltrate can adopt a very sparse perivascular and periadnexal distribution.…”
Section: Discussionmentioning
confidence: 99%
“…46 Morphologically, the malignant cells are centered in the dermis and can also extend into the subcutaneous tissue. The diagnosis can also be elusive because the infiltrate can adopt a very sparse perivascular and periadnexal distribution.…”
Section: Discussionmentioning
confidence: 99%
“…Miyeloid ve lenfoid lösemilerin en sık şekli leukemia cutis olarak isimlendirilir ve papül, nodül, plak ve/veya purpura varlığı ile kolaylıkla tanınabilir (10)(11)(12). Bu bulgular genellikle altta yatan akciğer, kolon, serviks gibi solid organ maligniteleri ve miyelodisplastik sendrom gibi hematolojik bozuklukların cilt reaksiyonları şeklinde ortaya çıkan kütanöz paraneoplastik sendromlardan farklıdır.…”
Section: Dermatopatik Lenfadenopati Ile Aml Birlikteliğiunclassified
“…Il y avait un très discret in ltrat périvasculaire et parfois interstitiel, peu spéci que, mais une cytologie attentive mettait en évidence des blastes monocytoïdes (le plus souvent CD68+ et parfois MPO+). Ce travail rappelle qu'un bon dermatopathologiste et quelques marqueurs peuvent conduire à un diagnostic précoce d'une LAM [39].…”
Section: éRuptions Anodinesunclassified