231 The Tolerability and Effectiveness of Duloxetine for the Prevention of Persistent Musculoskeletal Pain After Trauma and Injury: A Pilot Three-Group Randomized Controlled Trial
Abstract:Study Objectives: The primary aim was to examine the tolerability of duloxetine as a preventative treatment for emergency department (ED) patients who present with acute musculoskeletal pain after trauma or an injury. Tolerability was measured by drop-out rate and adverse effects. Secondary outcomes assessed drug effectiveness as measured by: (1) the proportion of participants with moderate to severe pain (numerical rating scale (NRS) > 4) at six weeks (pain persistence); (2) average pain by group over the six… Show more
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