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Sugihara, Ayako; Kajio, Keisuke; Yoshimoto, T; Tsujimura, Tohru; Iwasaki, Teruo; Yamada, Naoko; Terada, Nobuyuki; Tsuji, Motomu; Nojima, Masanori; Yabumoto, H; Mori, Yoshinori; Shima, Hiroki

doi:10.1023/a:1014400818905

Cited by 18 publications

(4 citation statements)

References 11 publications

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“…Carcinoid tumors primarily arise in the alimentary and lower respiratory tracts; whereas their genitourinary incidence in the testis, prostate, kidney, urethra, or urinary bladder is only encountered incidentally ( 6 ). Vesical carcinoid has a wide age distribution from 26 to 75 years.…”

Section: Discussionmentioning

confidence: 99%

“…The histogenesis of bladder carcinoids is debated as: Direct tumorigenesis from neuroendocrine cells, epithelial metaplasia, multipotential stem cell derivation, etc. Whatever may be the etiopathogenesis, these carcinoid cells generally express argyrophilia, with some extent of argentaffinity ( 6 ). Their neuroendocrine differentiation is best elicited by the immunohistochemical markers such as chromogranin, synaptophysin, and neuron-specific enolase ( 4 , 5 ).…”

Section: Discussionmentioning

confidence: 99%

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A Carcinoid Tumor in the Urinary Bladder With Uncommon Clinicopathological Presentation

Mondal¹,

Mandal²

2017

Iran J Pathol

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Background: Carcinoid tumors usually originate from the enterochromaffin cells located in gastrointestinal tract and bronchopulmonary system. They may rarely arise in the urinary bladder, where this can be eventually miscued as any other commoner bladder neoplasms. The current study was conducted to connote an uncommon clinicopathological presentation by a carcinoid tumor in the urinary bladder. Case: A 52-year-old male, who initially experienced obstructive urinary symptoms, underwent cystourethroscopy to remove a tumor in the urinary bladder. The tumor exhibited insular, trabecular, and organoid architecture on histology without any necrosis or mitosis, stained positively with chromogranin A, and thereby, confirmed the diagnosis of a pure carcinoid tumor. Conclusion: Carcinoid tumors rarely arise in the urinary bladder and other genitourinary organs. But, several other and relatively more common bladder neoplasms may often deceptively simulate it. This dilemma could be resolved easily with the application of proper immunohistochemistry (IHC) in neuroendocrine tumors.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A Carcinoid Tumor in the Urinary Bladder With Uncommon Clinicopathological Presentation

Mondal¹,

Mandal²

2017

Iran J Pathol

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“…The access catheters used in complex surgical operations have different structures depending on the target organ. These types of catheters can be referred to as surgical catheters, which contain diagnostic catheters and therapeutic catheters. − Surgical catheters can be used to diagnose and treat diseases of the urinary system, cardiovascular diseases of the circulatory system, diseases of the gastrointestinal and digestive system, and diseases of the nervous system. For example, surgical catheters used for minimally invasive urological diagnosis and treatment include ultrasound detection catheters for prostate cancer (Figure h), ablation catheters for bladder tumors, balloon catheters for stones, and microcatheters for the treatment of cystitis by drug injection, among others.…”

Section: Clinical Catheter-based Surgical Instrumentsmentioning

confidence: 99%

Advances in Multifunctional Electronic Catheters for Precise and Intelligent Diagnosis and Therapy in Minimally Invasive Surgery

Huang,

Liu

et al. 2024

ACS Nano

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The advent of catheter-based minimally invasive surgical instruments has provided an effective means of diagnosing and treating human disease. However, conventional medical catheter devices are limited in functionalities, hindering their ability to gather tissue information or perform precise treatment during surgery. Recently, electronic catheters have integrated various sensing and therapeutic technologies through micro/ nanoelectronics, expanding their capabilities. As micro/nanoelectronic devices become more miniaturized, flexible, and stable, electronic surgical catheters are evolving from simple tools to multiplexed sensing and theranostics for surgical applications. The review on multifunctional electronic surgical catheters is lacking and thus is not conducive to the reader's comprehensive understanding of the development trend in this field. This review covers the advances in multifunctional electronic catheters for precise and intelligent diagnosis and therapy in minimally invasive surgery. It starts with the summary of clinical minimally invasive surgical instruments, followed by the background of current clinical catheter devices for sensing and therapeutic applications. Next, intelligent electronic catheters with integrated electronic components are reviewed in terms of electronic catheters for diagnosis, therapy, and multifunctional applications. It highlights the present status and development potential of catheter-based minimally invasive surgical devices, while also illustrating several significant challenges that remain to be overcome.

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“…In surgery, ablation of bladder tissue can effectively remove bladder polyps, tumors, or ulcerated tissue. [46][47][48] Unlike other ablation systems based on heat or radiation that could easily cause non-target tissue necrosis, irreversible electroporation could permanently perforate cell membranes with an intensive electric field to induce cell death, which possesses advantages of clear ablation boundaries and less non-specific disruptions on non-target tissues. [49,50] The insertion of MN electrodes could form a tight coupling interface with tissue, which is beneficial to improve the efficiency of electroporation by bypassing the non-conductive mucosa layer (Figure 5e).…”

Section: Electrical Recording and Stimulation And Electroporation By ...mentioning

confidence: 99%

Petromyzontidae‐Biomimetic Multimodal Microneedles‐Integrated Bioelectronic Catheters for Theranostic Endoscopic Surgery

Huang

Yao

et al. 2023

Adv Funct Materials

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Current catheter devices in minimally invasive surgery still possess limited functional options, lacking multimodal integration of both sensing and therapy. Catheter devices usually operate outside the tissue, incapable to detect intra‐tissue biochemical information for accurate localization and assessment of lesions during surgery. Inspired by the feature and functions of Petromyzontidae, here a multimodal core‐shell microneedles‐integrated bioelectronic catheter (MNIBC) for tissue‐penetrating theranostics in endoscopic surgery is developed. The microneedle (MN) device possesses individually addressable functionality at single‐MN tip resolution, enabling multiplex functions (a total of 11 functions distributed in three types of catheters) including biochemical sensing, myoelectric modulation, electroporation, and drug delivery in a submucosal environment. The MNIBC is prepared through hybrid fabrication and dimensionality reduction strategies, where the MN electrodes are functionalized with an MXene‐carbon nanotube (MXene‐CNT)‐based electron mediator, addressing the challenge of reduced electrode sensitivity on ultra‐small MN tip. The functionalities of MNIBC are demonstrated both ex vivo and in vivo on anesthetized rabbits via laparoscopy, simulated cystoscopy, and laparotomy. The MNIBC can effectively detect intra‐tissue biochemical signals in the bladder, and offers localized electroporation and intra‐tissue drug delivery for precise treatments of lesions. The versatile features of the MNIBC present a highly advanced platform for precise surgeries.

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Cited by 18 publications

References 11 publications

A Carcinoid Tumor in the Urinary Bladder With Uncommon Clinicopathological Presentation

A Carcinoid Tumor in the Urinary Bladder With Uncommon Clinicopathological Presentation

Advances in Multifunctional Electronic Catheters for Precise and Intelligent Diagnosis and Therapy in Minimally Invasive Surgery

Petromyzontidae‐Biomimetic Multimodal Microneedles‐Integrated Bioelectronic Catheters for Theranostic Endoscopic Surgery

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