Anti-Staphylococcus aureusaction of three Caatinga fruits evaluated by electron microscopy

Abstract

This study evaluated the antibacterial activity of Anadenanthera colubrina, Libidibia ferrea and Pityrocarpa moniliformis fruit extracts against clinical strains of Staphylococcus aureus. The samples were active for all S. aureus strains (minimum inhibitory concentration: 0.38-3.13 mg mL⁻¹), including the multiresistant strain. The morphological changes suggested the cell wall as the main action target. The treated-cells also lose their ability to form aggregates. The analysis suggests cell wall impairment, which causes the loss of viability and death. This study showed for the first time the morphologic alterations involved in the anti-S. aureus action of fruits of A. colubrina, L. ferrea and P. moniliformis. These findings indicated that these fruit extracts are sources of bioactive compounds that can be used as antibacterial agents.

Effects of Rainfall on the Antimicrobial Activity and Secondary Metabolites Contents of Leaves and Fruits of Anadenanthera colubrina from Caatinga Area

“…[4][5][6][7]12,17 In our previous studies the antimicrobial action of extracts and fractions from leaves and fruits of A. colubrina was reported against Gram-positive bacteria, and no activity was observed against Gram negative bacteria. [4][5][6]12 In the present work we employed a different extraction method, by which we obtained extracts with activity against tested Gram negative bacteria. Anyway, the best activity was found against S. aureus and B. subtilis, and ethyl acetate extracts had the best activity.…”

“…2,3 For some of those, scientific evidences confirm these therapeutic aptitudes. [4][5][6][7] In recent years, the ethnomedicinal knowledge has stimulated several studies about the pharmaceutical potential of natural products of northeastern Brazil. 8 This is justified by the fact that the intrinsic features of Caatinga area (drought, high solar radiation rates and other environmental stresses) influence the synthesis of secondary metabolites of its plants, 9 making them attractive targets for bioprospecting programs.…”

“…2,3 Previous studies demonstrated the antimicrobial potential of leaves and fruits of this plant, especially against Staphylococcus aureus. [4][5][6]12 In this context, the present study aims to analyze the effects of rainfall on the antimicrobial activity and secondary metabolites contents of leaves and fruits of Anadenanthera colubrina. With this information, the best collection time to maximize the bioactive compounds extraction for medicinal purposes may be determined.…”

Syagrus coronata seed oils have antimicrobial action against multidrug-resistant Staphylococcus aureus

“…It supports a great diversity of plant species (Albuquerque et al, 2012). As a result of the environmental conditions to which they are exposed, Caatinga plants have developed interesting chemical features, some of which have been described as excellent weapons against microorganisms (Castelo Branco Rangel de Almeida et al, 2012;Oliveira et al, 2012;Da Silva et al, 2013).…”

Spermostatic activity of Eugenia brejoensis and Myroxylon peruiferum essential oils toward human spermatozoa

“…It is believed that these climatic features play an essential role in the production of bioactive metabolites by plants of the Caatinga (de Albuquerque et al, 2012). Such metabolites provide a range of proven biomedical applications (de Oliveira et al, 2012;da Silva et al, 2013), thereby encouraging the search for new compounds from plants of the Caatinga.…”