Abstract:The reprogramming process suffers from effects of external and internal factors, one of which is oxygen concentration, because it plays important roles in several processes of the cell. The objective of this study was to evaluate the effect of oxygen during reprogramming of equine adult fibroblasts. Fibroblasts were isolated from the skin of one male and immediately cultured under high (20%, HO group) or low (5%, LO group) oxygen tension. Generation of induced pluripotent stem cells (iPSCs) was performed by tr… Show more
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