“…Adults may not tolerate prolonged high-dose corticosteroids well, and with the protracted natural history of primary FSGS, the side effects of corticosteroids may be unacceptable to some patients. 336 Additionally, patients who are obese, have uncontrolled diabetes, psychiatric conditions, or severe osteoporosis may be deemed to have a relative contraindication to corticosteroids. Ideally, such patients would be considered for an alternative treatment to corticosteroids.…”