206 Bone quality at the time of lung transplant in cystic fibrosis patients

Bone health and disease in cystic fibrosis

“…Bone histomorphometry studies suggest that osteoporosis is the major pathology in CF related bone disease, although osteomalacia is seen (11,12). A recent study of bone specimens obtained from 17 patients with CF at the time of lung transplantation and 21 donor controls found reduced osteoid parameters in the CF group suggesting decreased osteoblast activity, regardless of glucocorticoid and / or bisphosphonate use (13).…”