2022 Esc Guidelines for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: What is New?

Novikova, Tatiana N.; Novikov, V. I.; Sayganov, Sergey A.

doi:10.17816/cardar110961

Cited by 3 publications

(3 citation statements)

References 97 publications

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“…Current guidelines [ 83 ] recommend the use of immunosuppressive therapy in selected cases of virus-negative biopsy-proven myocarditis, on top of OMT that should be targeted on the specific patient’s phenotype, e.g., anti-HF drugs in case of left ventricular dysfunction or antiarrhythmic medical therapy in case of hemodynamically stable sustained ventricular arrhythmias [ 132 ].…”

Section: Discussionmentioning

confidence: 99%

The Role of the Immune System in Pathobiology and Therapy of Myocarditis: A Review

Vicenzetto,

Giordani,

Menghi

et al. 2024

Biomedicines

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The role of the immune system in myocarditis onset and progression involves a range of complex cellular and molecular pathways. Both innate and adaptive immunity contribute to myocarditis pathogenesis, regardless of its infectious or non-infectious nature and across different histological and clinical subtypes. The heterogeneity of myocarditis etiologies and molecular effectors is one of the determinants of its clinical variability, manifesting as a spectrum of disease phenotype and progression. This spectrum ranges from a fulminant presentation with spontaneous recovery to a slowly progressing, refractory heart failure with ventricular dysfunction, to arrhythmic storm and sudden cardiac death. In this review, we first examine the updated definition and classification of myocarditis at clinical, biomolecular and histopathological levels. We then discuss recent insights on the role of specific immune cell populations in myocarditis pathogenesis, with particular emphasis on established or potential therapeutic applications. Besides the well-known immunosuppressive agents, whose efficacy has been already demonstrated in human clinical trials, we discuss the immunomodulatory effects of other drugs commonly used in clinical practice for myocarditis management. The immunological complexity of myocarditis, while presenting a challenge to simplistic understanding, also represents an opportunity for the development of different therapeutic approaches with promising results.

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Section: Discussionmentioning

confidence: 99%

The Role of the Immune System in Pathobiology and Therapy of Myocarditis: A Review

Vicenzetto,

Giordani,

Menghi

et al. 2024

Biomedicines

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“…The diagnosis of ACM is complex and requires searching and assessing certain criteria. Although the recommendations contain a reference in Guidelines 2022 to the publication of Corrado et al (2020) [28], the criteria for diagnosing ACM are not the 2020 Padua criteria but the previous 2010 criteria [32]. As an advantage, the Padua criteria provide an algorithm for diagnosing not only the right ventricular but also the LV process.…”

Section: Arrhythmogenic Right Ventricular Cardiomyopathy (Acm)mentioning

confidence: 99%

European guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death 2022: cardiomyopathy. What’s new?

Novikova,

Bitakova,

Ignateva

et al. 2024

Cardiac Arrhythmias

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The review provides information on new indications that should be guiden the diagnosis and treatment of ventricular arrhythmias in patients with cardiomyopathy. The analysis of modern definitions and classifications of cardiomyopathy is given. The issues of ventricular arrhythmias in different cardiomyopathy phenotypes, risk stratification of sudden cardiac death and its prevention are considered in detail.

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“…Неустойчивая и устойчивая ЖТ -частая находка у пациентов, страдающих ГКМП . В связи с высоким риском ВСС при этой патологии требуются стратификация степени риска и определение показаний к установке ИКД [1,3,11,12] . Наличие у нашего пациента устойчивых ЖТ, сопровождающихся нарушениями гемодинамики, потребовало установки ИКД в 2007 году и замен в 2012 и 2020 годах в связи с истощением заряда батареи .…”

Section: Cardiac Arrhythmiasunclassified

Multifaces of hypertrophic cardiomyopathy: a case of transformation of hypertrophic phenotype into dilated

Novikova,

Andreeva,

Bitakova

et al. 2024

Cardiac Arrhythmias

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The article presents a clinical case of a rather rare course of hypertrophic cardiomyopathy with the transformation of a hypertrophic phenotype into a dilated phenotype against the background of the “burned-out phase” phenomenon, ventricular and supraventricular rhythm disturbances, and multiple genetic mutations. Timely started disease-modifying therapy (quadruple therapy) for chronic heart failure led to reverse positive remodeling of the left chambers of the heart.

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2022 Esc Guidelines for the Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: What is New?

Cited by 3 publications

References 97 publications

The Role of the Immune System in Pathobiology and Therapy of Myocarditis: A Review

The Role of the Immune System in Pathobiology and Therapy of Myocarditis: A Review

European guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death 2022: cardiomyopathy. What’s new?

Multifaces of hypertrophic cardiomyopathy: a case of transformation of hypertrophic phenotype into dilated

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