Background: Supraventricular Tachycardia (SVT) is the most frequent arrhythmia requiring a medical treatment in neonates. Objectives: The aim of our study was to evaluate and manage neonatal supraventricular tachycardia. Methods: This study was performed on 22 newborns that were diagnosed with SVT at two neonatal intensive care units (NICU) in south west of Iran from October 2012 to October 2015. Data on gender, age, weight, maternal age, gestational age, presence of congenital heart disease, blood pressure in admission, duration of hospitalization period, duration of SVT, medicine for the control of SVT, list of medicine administered at releasing time were collected. Echocardiography was performed for all patients. Data was analyzed by the SPSS version 18 software.