2013 ESH/ESC Guidelines for the Management of Arterial Hypertension: What Has Changed in Daily Clinical Practice?

Liakos, C.; Grassos, Charalampos; Babalis, Dimitrios

doi:10.1007/s40292-014-0071-2

Cited by 21 publications

(13 citation statements)

References 9 publications

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“…dyslipidemia was defined according to the ESC recommendations (Guidelines for the Management of Dyslipidemias). [7][8][9] The degrees of stenosis of the common carotid artery and/or internal carotid artery were assessed according to the NASCET criteria. [10] Blood BDNF, Il-2, IL-6, S100B, TNF, GRN, NSE, uPA, VEGF concentrations on day 1 of stroke were assessed according to procedure as follows: 7 ml of EDTA blood was drawn and plasma was obtained after 15 minutes of centrifugation (1500 rpm), then the plasma was frozen at -80°C.…”

Section: Methodsmentioning

confidence: 99%

The importance of selected markers of inflammation and blood-brain barrier damage for short-term post-stroke prognosis

Lasek–Bal

Jędrzejowska–Szypułka

Student

et al. 2018

Preprint

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Acute cerebral ischemia triggers local and systemic immune response. The aims of this project was to assess the blood serum concentration of the markers of inflammation and markers of the blood brain barrier damage on the first day of ischemic stroke, and the mutual correlations between these marker levels. Methods Our prospective study included 138 patients with first-in-life stroke, who were analyzed according to: plasma concentration of the following markers on the first day of stroke: Il-2 and IL-6, S100B, TNF alfa, GRN, NSE, uPA, VEGF, BDNF, CRP, leucocyte and thrombocyte counts; their neurological status on the first day of stroke (NIHSS) and their functional status at 30 days following stroke (mRS). Result The study included 138 patients with mean age: 73.11 ± 11.48 [36-103]. Patients with a higher score on the NIHSS than those obtaining lower scores showed significantly higher concentrations of TNF-alpha, WBC, CRP, NSE, IL-6 and S100B. Patients with a higher score on the mRS than those obtaining lower scores showed significantly higher concentrations of WBC, CRP, GRN, IL-6, S100B. Factors with an independent influence on the neurological status on the first day of stroke were: sex, WBC, PLT, CRP, S100B and IL-6 levels. Atrial fibrillation, leukocyte count, CRP, NSA, uPA, interleukin 6 and S100B showed an independent impact on the functional status on the 30th day of stroke. Patients with symptomatic atherosclerosis of carotid/cerebral and/or coronary arteries, as compared to others, were older (p= 0.003) and had higher levels of CRP, Il-6, and S100B. In each case, the differences were statistically significant. Conclusions The concentration of Il-6 and S100B on the first day of stroke are significant for both the neurological status and the functional status in the acute period of the disease. Increased CRP and leukocyte count are associated with a worse prognosis regarding the course of acute stroke. The expression of pro-inflammatory agents and markers of blood-brain barrier damage in the acute phase of stroke is more prominent in patients with symptomatic atherosclerosis than in patients with no clinical features of atherosclerosis.

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Section: Methodsmentioning

confidence: 99%

The importance of selected markers of inflammation and blood-brain barrier damage for short-term post-stroke prognosis

Lasek–Bal

Jędrzejowska–Szypułka

Student

et al. 2018

Preprint

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“…Initially, the criteria were met by 61 patients, 29 patients were enrolled in the study, and the results of 13 patients were included in the preparatory analysis presented in the preliminary report. All the patients included in the study were analyzed according to: their age at the first-in-life stroke onset; the presence of comorbidities such as: atrial fibrillation (AF), arterial hypertension (AH), coronary heart disease (CHD), diabetes mellitus (DM) and lipid disorders (LD), >70% atherosclerotic carotid stenosis (ipsilaterally to the acute ischemic brain lesion) according to NASCET [2]; their neurological status on the first day after stroke onset evaluated according to the National Institute of Health Stroke Scale (NIHSS) [3]; the location of the stroke (total anterior cerebral infarct, TACI); partial anterior CI (PACI), lacunar CI (LACI) and posterior CI (POCI) [4]; early therapeutic management in the acute stage of stroke (recombinant tissue plasminogen activator [iv rtPA], endovascular, antiplatelet treatment); their functional status at 14 days after stroke according to mRS [5]. fMRI of the head up to 4th day of stroke…”

Section: Methodsmentioning

confidence: 99%

BOLD fMRI signal in stroke patients and its importance for prognosis in the subacute disease period – Preliminary report

Lasek–Bal

Kidoń

Błaszczyszyn

et al. 2018

Neurologia i Neurochirurgia Polska

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There are differences observed in the activation areas of the cerebral cortex both in the stroke and non-stroke hemispheres. More than half of the patients with hemispheric stroke but all with good outcome showed cerebellar activation. There is probable positive correlation between the BOLD-signal size, young age, activation of supplementary motor area in stroke hemisphere and good functional status of patients in the subacute period of stroke.

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“…The eGFR calculation obtained from SC was based on the Levey modified Modification of Diet in Renal Disease formula as 186 × SC −1.154 × age −0.203 × 0.742 (if female) (Foundation National Kidney, 2002). A systolic blood pressure > 140/ 90 mm Hg obtained by at least two separate measurements during hospitalization, a previously diagnosed hypertension or history of antihypertensive medications was regarded as hypertension (Liakos et al, 2015;Mancia et al, 2007), while DM was defined as either preexisting diagnosed disease or at least two fasting blood glucose levels higher than 7.0 mmol/l or two-hour plasma glucose levels higher than 11.1 mmol/l by oral glucose tolerance test (Ryden et al, 2007). CIAKI referred to an absolute increase of 0.5 mg/dl (44.2 µmol/l) and/or a 25% increase in SC concentration from baseline value of contrast agent administration to 72 h in the absence of alternative explanation for acute kidney injury (AKI) (Silvain et al, 2014).…”

Section: Study Protocolmentioning

confidence: 99%

Serum albumin and the risk of contrast-induced acute kidney injury after percutaneous coronary intervention

Sun

et al. 2020

Reviews in Cardiovascular Medicine

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Serum creatinine and serum albumin levels were measured prior to surgery, and serum creatinine level was also measured at 72 hours following percutaneous coronary intervention in 819 (January 1 st , 2015 and December 31 st , 2018). According to whether patients developed contrastinduced acute kidney injury or not, they were assigned to either a contrast-induced acute kidney injury group (72 cases, 8.8%) or a non-contrast-induced acute kidney injury group (747 cases; control).Serum albumin was significantly lower in the contrast-induced acute kidney injury group than control (39.33 ± 5.09 g/l and 42.69 ± 5.19 g/l, respectively, P < 0.001). The results of a receiveroperating curve analysis indicated a serum albumin level of 40.5 g/L was the optimal cutoff value for prediction of contrast-induced acute kidney injury and according to a multivariate logistic regression analysis, serum albumin was an independent biomarker for prediction of (95% confidence interval: 0.836-0.935, odds ratio: 0.884, P < 0.001). Serum albumin, a low-cost and easily assessable laboratory protein, was independently related to a greater risk of contrast-induced acute kidney injury among patients that received percutaneous coronary intervention. It is proposed that under these circumstances SA is a potential biomarker for contrast-induced acute kidney injury.

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2013 ESH/ESC Guidelines for the Management of Arterial Hypertension: What Has Changed in Daily Clinical Practice?

Cited by 21 publications

References 9 publications

The importance of selected markers of inflammation and blood-brain barrier damage for short-term post-stroke prognosis

The importance of selected markers of inflammation and blood-brain barrier damage for short-term post-stroke prognosis

BOLD fMRI signal in stroke patients and its importance for prognosis in the subacute disease period – Preliminary report

Serum albumin and the risk of contrast-induced acute kidney injury after percutaneous coronary intervention

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