2008
DOI: 10.1161/circulationaha.107.188208
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2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention

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Cited by 703 publications
(183 citation statements)
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References 181 publications
(119 reference statements)
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“…Hydration also reduces the direct toxic effects of the contrast agent on the kidney by diluting and decreasing its viscosity in the renal tubules [8,9]. A meta-analysis of six trials demonstrated that oral hydration with a pre-specified expansion volume is as effective as intravenous for the prevention of contrast-induced nephropathy.…”
Section: Discussionmentioning
confidence: 99%
“…Hydration also reduces the direct toxic effects of the contrast agent on the kidney by diluting and decreasing its viscosity in the renal tubules [8,9]. A meta-analysis of six trials demonstrated that oral hydration with a pre-specified expansion volume is as effective as intravenous for the prevention of contrast-induced nephropathy.…”
Section: Discussionmentioning
confidence: 99%
“…Previous studies 34 -37 have reported that the cytochrome P450 2C19 polymorphism, diabetes mellitus, sex, smoking status, and renal insufficiency were significant predictors of P2Y 12 inhibition after clopidogrel administration. 18 An association of a history of CHD with the response to clopidogrel has not been demonstrated. Randomization is a method based on chance alone by which study participants are assigned to different trial arms.…”
Section: Discussionmentioning
confidence: 99%
“…18 Patients who concomitantly used anticoagulant agents were also excluded. Patients who had hypersensitivity to aspirin or clopidogrel, a serious bleeding tendency, a history of intracranial hemorrhage, signs of active bleeding, or uncontrolled hypertension were not included.…”
Section: Inclusion and Exclusion Criteriamentioning
confidence: 99%
“…Subsequent studies extend on the indications for its use in the setting of acute coronary syndromes (ACS) [2], ST-segment elevation myocardial infarction [3,4] and percutaneous coronary intervention (PCI) [5,6]. Despite the robust clinical findings and indications for clopidogrel usage derived from these large-scale clinical trials performed over the course of the past decade, which are clearly reflected in clinical practice guidelines [7][8][9], there are a large number of uncertainties regarding clopidogrel usage in daily real world practice. This is reflected by the plethora of publications dealing with clopidogrel over the course of the past several years.…”
mentioning
confidence: 99%
“…Other studies have confirmed these findings that are in line with the more rapid and potent effects of this dosing regimen, and which now represents the loading dose of choice by most interventionalists. Importantly, the updated PCI guidelines have recently provided a class I indication for a 600 mg dosing regimen, even though the data to support this are limited to relatively small samplesized studies [9]. It is for this reason that a 600 mg clopidogrel dose is not approved by regulatory authorities.…”
mentioning
confidence: 99%