2-Sulfanilyl-aminothiazoline

Abstract

Vol. (S3 point determination. Check runs, with longer reaction periods, were made to check the completeness of the reaction. It is apparent from the analyses that, under the conditions used in this work, there is no tendency for the salts to form crystalline ammines with the excess ammonia gas present.

Thiazolidinones: Synthesis, Reactivity, and Their Biological Applications

“…The acid hydrolysis of 2‐iminothiazolidines ( 5 ) gives the corresponding 2‐thiazolidinones ( 6 ) in good yield . …”

“…The acid hydrolysis of 2-iminothiazolidines (5) gives the corresponding 2-thiazolidinones (6) in good yield [12]. The treatment of 2-aminoethyl benzyl dithiocarbamate hydrochloride with 1 N NaOH solution, followed by neutralization with HCl, resulted in the formation of 2thiazolidinones ( Fig.…”

“…The 1 H nuclear magnetic resonance (NMR) spectra of all derivatives show a multiplet at δ 3.83-4.05 due to the diastereotopic protons of the 4-thiazolidinone ring (─CH 2 at the 5th position), and in the 13 C NMR, the carbonyl carbon C-4 of the thiazolidinone ring appears at δ 170.0-171.9. The NMR spectra of 2-imino-4-oxothiazolidinyl-5acetates (11) and 2,4-dioxothiazolidine-5-acetates(12) show characteristic patterns of an ABX system[46]. The chemical shifts of the protons H a , H b , and H x have been assigned at about 3.09-3.35, 2.78-3.07, and 4.36-4.60 ppm, respectively, and indicate that the methylene protons adjacent to an asymmetric center are magnetically nonequivalent.…”

Relationships between the Structure and the Bactericidal Properties of Phenols.

“…The compounds obtained by condensing "amylene" (30) or an amyl alcohol (57,142) with a cresol have also been described as useful bactericides. Other patents have dealt with the general preparation of secondary or tertiary alkylcresols (24,115) as compounds having germicidal properties. Raiziss and Clemence (115) have suggested that the condensation of a cresol with 2-methyl-l-butanol may give the primary alkylcresol, but this is unlikely in view of the results reported in condensations involving phenol.…”

“…However, because carvacrol and thymol are readily available, chlorine derivatives of these have been advocated for use as germicidal agents (111,112,129). Chlorine derivatives of the amylcresols have also been described in the patent literature (114).…”