2. Outlook

Elmadfa, Ibrahim

doi:10.1159/000242367

Cited by 26 publications

(17 citation statements)

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“…The observed mean folate intake in this review (266 μg/day) is in line with intakes indicated by individual observational studies that assessed folate intake in adults and elderly in Europe: the mean folate intake for adults and elderly in the European Nutrition and Health Report (25 countries) ranged from 130 to 370 μg/day in women and from 150 to 440 μg/day in men [44], whereas the results from the EPIC cohort (10 countries) reported 200–300 μg/day in women and 250–350 μg/day in men [45]. The levels of serum/plasma folate reported in a recent publication on micronutrient intake and status is Europe were 14–23 nmol/L [46], and in the publication by Duffy et al [3], the levels were in the range 6–24 nmol/L and this is in line with the range observed in this review (5–31 nmol/L).…”

Section: Discussionsupporting

confidence: 77%

Systematic Review of Observational Studies with Dose-Response Meta-Analysis between Folate Intake and Status Biomarkers in Adults and the Elderly

et al. 2018

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Background: Dietary reference values for folate intake vary widely across Europe. Methods: MEDLINE and Embase through November 2016 were searched for data on the association between folate intake and biomarkers (serum/plasma folate, red blood cell [RBC] folate, plasma homocysteine) from observational studies in healthy adults and elderly. The regression coefficient of biomarkers on intake (β) was extracted from each study, and the overall and stratified pooled β and SE (β) were obtained by random effects meta-analysis on a double log scale. These dose-response estimates may be used to derive folate intake reference values. Results: For every doubling in folate intake, the changes in serum/plasma folate, RBC folate and plasma homocysteine were +22, +21, and –16% respectively. The overall pooled regression coefficients were β = 0.29 (95% CI 0.21–0.37) for serum/plasma folate (26 estimates from 17 studies), β = 0.28 (95% CI 0.21–0.36) for RBC (13 estimates from 11 studies), and β = –0.21 (95% CI –0.31 to –0.11) for plasma homocysteine (10 estimates from 6 studies). Conclusion: These estimates along with those from randomized controlled trials can be used for underpinning dietary recommendations for folate in adults and elderly.

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Section: Discussionsupporting

confidence: 77%

Systematic Review of Observational Studies with Dose-Response Meta-Analysis between Folate Intake and Status Biomarkers in Adults and the Elderly

et al. 2018

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“…The actual diet of the Lithuanian high-performance athletes was estimated using a 7-day food recall survey method [34,35]. The survey was performed by a trained interviewer using the direct interview method at the Lithuanian Sports Centre.…”

Section: Dietary Intakementioning

confidence: 99%

Cardiorespiratory Fitness and Diet Quality Profile of the Lithuanian Team of Deaf Women’s Basketball Players

Baranauskas

Jablonskienė

Abaravičius

et al. 2020

IJERPH

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There are about 466 million people with hearing impairments in the world. The scientific literature does not provide sufficient data on the actual nutrition and other variables of professional deaf athletes. The objectives of this study were to investigate and evaluate the body composition, the physical working capacity, the nutrition intake, and the blood parameters of iron and vitamin D in the Lithuanian high-performance deaf women’s basketball team players. The female athletes (n = 14) of the Lithuanian deaf basketball team aged 26.4 ± 4.5 years were recruited for an observational cross-sectional study. A 7-day food recall survey method was used to investigate their actual diet. The measurements of the body composition were performed using the BIA (bioelectrical impedance analysis) tetra-polar electrodes. In order to assess the cardiorespiratory and aerobic fitness levels of athletes, ergo-spirometry (on a cycle ergometer) was used to measure the peak oxygen uptake (VO2peak) and the physical working capacity at a heart rate of 170 beats per minute (PWC170). The athletes’ blood tests were taken to investigate the red blood cells, hemoglobin, 25-hydroxyvitamin D, ferritin, transferrin, iron concentrations, and total iron-binding capacity (TIBC). The consideration of the VO2peak (55.9 ± 6.1 mL/min/kg of body weight, 95% CI: 51.8, 58.9) and the low VO2peak (56–60 mL/min/kg of body weight) (p = 0.966) in the deaf women’s basketball team players revealed no differences. For the deaf female athletes, the PWC170 was equal to 20.3 ± 2.0 kgm/min/kg of body weight and represented only the average aerobic fitness level. The carbohydrate and protein intakes (5.0 ± 1.3 and 1.3 ± 0.3 g/kg of body weight, respectively) met only the minimum levels recommended for athletes. The fat content of the diet (38.1 ± 4.1% of energy intake) exceeded the maximum recommended content (35% of energy intake) (p = 0.012). The mean blood serum concentrations of 25(OH)D and ferritin (24.1 ± 6.6 nmol/L and 11.0 ± 4.1 µg/L, respectively) predicted vitamin D and iron deficits in athletes. Female athletes had an increased risk of vitamin D and iron deficiencies. Regardless of iron deficiency in the body, the better cardiorespiratory fitness of the deaf female athletes was essentially correlated with the higher skeletal muscle mass (in terms of size) (r = 0.61, p = 0.023), the lower percentage of body fat mass (r = −0.53, p = 0.049), and the reduced intake of fat (r = −0.57, p = 0.040).

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“…This puts the French into the middle range of intakes within Europe: The European Nutrition and Health Survey reports mean vitamin C intakes ranging from ~60 mg to ~153 mg [110]. However, the informative value of mean intakes is limited when assessing the adequacy of intake of a population: despite the comparatively high mean intake reported for Germany (153 mg/day for adults) [110], half the adult population has vitamin C intake below 100 mg/day, which was the recommendation at the time of the survey [59,111,112].…”

Section: Vitamin C Status In the General Populationmentioning

confidence: 99%

“…However, the informative value of mean intakes is limited when assessing the adequacy of intake of a population: despite the comparatively high mean intake reported for Germany (153 mg/day for adults) [110], half the adult population has vitamin C intake below 100 mg/day, which was the recommendation at the time of the survey [59,111,112]. Using a lower level of 60 mg/day and 50 mg/day for men and women, respectively, the European survey reports on 8% to 40% of adults with inadequate intakes [113], and similar rates were reported in the U.S. [114].…”

Section: Vitamin C Status In the General Populationmentioning

confidence: 99%

Emerging Evidence on Neutrophil Motility Supporting Its Usefulness to Define Vitamin C Intake Requirements

Elste¹,

Troesch²,

Eggersdorfer³

et al. 2017

Nutrients

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Establishing intake recommendations for vitamin C remains a challenge, as no suitable functional parameter has yet been agreed upon. In this report, we review the emerging evidence on neutrophil motility as a possible marker of vitamin C requirements and put the results in perspective with other approaches. A recent in vitro study showed that adequate levels of vitamin C were needed for this function to work optimally when measured as chemotaxis and chemokinesis. In a human study, neutrophil motility was optimal at intakes ≥250 mg/day. Interestingly, a Cochrane review showed a significant reduction in the duration of episodes of common cold with regular vitamin C intakes in a similar range. Additionally, it was shown that at a plasma level of 75 µmol/L, which is reached with vitamin C intakes ≥200 mg/day, incidences of cardiovascular disease were lowest. This evidence would suggest that daily intakes of 200 mg vitamin C might be advisable for the general adult population, which can be achieved by means of a diverse diet. However, additional studies are warranted to investigate the usefulness of neutrophil motility as a marker of vitamin C requirements.

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2. Outlook

Cited by 26 publications

References 0 publications

Systematic Review of Observational Studies with Dose-Response Meta-Analysis between Folate Intake and Status Biomarkers in Adults and the Elderly

Systematic Review of Observational Studies with Dose-Response Meta-Analysis between Folate Intake and Status Biomarkers in Adults and the Elderly

Cardiorespiratory Fitness and Diet Quality Profile of the Lithuanian Team of Deaf Women’s Basketball Players

Emerging Evidence on Neutrophil Motility Supporting Its Usefulness to Define Vitamin C Intake Requirements

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