(2-Methylphenyl)(phenyl)methanol

Abstract

In the title compound, C14H14O, the two benzene rings are almost orthogonal [dihedral angle = 87.78 (8) °]. The hy­droxy group lies approximately in the plane of its attached benzene ring [O—C—C—C torsion angle = −17.47 (17)°], and the hydroxyl and methyl groups lie to the same side of the mol­ecule and are gauche to each other. In the crystal, a hexa­meric aggregate mediated by a ring of six O—H⋯O hydrogen bonds occurs, generating an R 6 6(12) loop.

2-(2-Benzylphenyl)propan-2-ol

“…Benzhydrols are widely used as intermediates for the synthesis of pharmaceuticals (Ohkuma et al, 2000). The crystal structures of 2-(5-bromo-2-methylphenyl)propan-2-ol (Zeng & Liu, 2010), 10,10-dimethylanthrone (Fun et al, 2010), (2-methylphenyl)(phenyl)methanol (Siddaraju et al, 2010), 9,9-dimethyl-9,10-dihydroanthracene (Siddaraju et al, 2011) and a N,N-dimethylamino-substituted analogue of the title compound (Gu et al, 2009) have been reported earlier. In view of the importance of the title compound, its crystal structure was determined.…”

“…For general background to the use of benzhydrols in pharmaceutical synthesis, see: Ohkuma et al (2000). For related structures, see: Ferguson et al (1995); Fun et al (2010); Siddaraju et al (2010Siddaraju et al ( , 2011; Zeng & Liu (2010); Gu et al (2009). For graph-set analysis of hydrogen bonds, see: Etter et al (1990); Bernstein et al (1995).…”

Methyl 2,2-diphenyl-2-(prop-2-yn-1-yloxy)acetate

“…For related literature on the background of this work, see: Ferguson et al (1995); Ohkuma et al (2000). For related structures, see: Narayanan et al (2011); Shah et al (2011); Siddaraju et al (2010); Zhang et al (2008); Zhang et al (2011). Data collection: SMART (Bruker, 2002); cell refinement: SAINT (Bruker, 2002); data reduction: SAINT; program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL and local programs.…”

2-[(2-Chlorophenyl)(hydroxy)methyl]phenol

“…For the use of the title compound in the perfume and pharmaceutical industries, see: Meguro et al (1985). For related diphenylmethanol structures, see: Betz et al (2011); Ferguson et al (1995); Siddaraju et al (2010). Table 1 Hydrogen-bond geometry (Å , ).…”

“…Recently, the crystal structure of (2-methylphenyl) (phenyl)methanol (Siddaraju et al, 2010) and 2-(2-benzylphenyl)…”