2-Ethylhexyl Diphenyl Phosphate Causes Obesity in Zebrafish by Stimulating Overeating via Inhibition of Dopamine Receptor D2
Rongyan Yang,
Yuan Zhang,
Yun Deng
et al.
Abstract:Obesity is a popular public health problem worldwide
and is mainly
caused by overeating, but little is known about the impacts of synthetic
chemicals on obesity. Herein, we evaluated the obesogenic effect caused
by 2-ethylhexyl diphenyl phosphate (EHDPHP) on zebrafish. Adult zebrafish
were exposed to 5, 35, and 245 μg/L of EHDPHP for 21 days. Results
showed that EHDPHP exposure significantly promoted the feeding behavior
of zebrafish, as evidenced by shorter reaction time, increased average
food intake, feedin… Show more
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