2′-Deoxyadenosine Adducts with 3d Metal Perchlorates

5?-Deoxyadenosine complexes with chromium(III) and iron(III) perchlorates

“…Unlike ado and 2'-dado, which have so far been found only to form exclusively adducts with 3d metal salts (2)(3)(4), 5'-deoxyadenosine gives complexes formed by substitution of three monoanionic L-ligands for three C10~ groups per two metal ions. Monodeprotonation of the exocyclic NH2 group of nucleobases, such as adenine and cytosine, and their nucleosides is not generally facile (8), but can (reportedly) occur in some cases, e.g.…”

“…complexes in which the ligands remain formally neutral) with first row transition metal halides or perchlorates (2)(3)(4). Recently, we extended our studies to include complexes with 5'-deoxyadenosine [dado; LH; (1)], which had previously been investigated as a ligand only in 5'-deoxyadenosylcobaloxime complexes ~5'6).…”