2-Acylthioacetamides in the Biginelli Reaction

Kurmach, M. M.; Ryabitskiy, A. B.; Britsun, V. N.

doi:10.1007/s10593-014-1429-z

Search citation statements

Order By: Relevance

Paper Sections

Select...

Pyrimidine Derivatives1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2014

2023

Publication Types

Select...

Article4

Book2

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 10 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, a Biginellitype reaction was developed by Britsun and coworkers to synthesize tetrahydropyrimidine-5-carbothioamides through β-ketothioamide, aryl aldehyde and ureas or thioureas (Scheme 14). 27 Interestingly, the reactions did not proceed in the absence of boric acid. The aldehydes with electron-donating groups on the aryl ring gave higher yields (70-72%) than those with electron-withdrawing groups (51-58%).…”

Section: Pyrimidine Derivativesmentioning

confidence: 99%

β-Ketothioamides: efficient reagents in the synthesis of heterocycles

Guo

Wen

2015

Org. Biomol. Chem.

View full text Add to dashboard Cite

β-Ketothioamides (KTAs) are versatile building blocks for the rapid construction of various heterocyclic compounds. In the past decade, a number of successful reactions based on KTAs have been developed for the construction of heterocyclic skeletons under mild conditions. This minireview focuses on the annulation reactions of KTAs with dielectrophilic or dinucleophilic reagents. Multicomponent reactions using KTAs to construct various heterocycles are also the major contents in this review.

show abstract

Section: Pyrimidine Derivativesmentioning

confidence: 99%