2-Acyl-1-aryl-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazole derivatives: Versatile fluorescent probes with remarkably large Stokes shift

A mitochondria-targeting “off–on” AIE probe with large Stokes shift for high-contrast H2S imaging in living cells

“…Therefore, developing a H 2 S probe with a large Stokes shift can be helpful to reduce background interference, avoid self-quenching phenomena and improve the signal-to-background ratio of imaging. [40][41][42] Therefore, probe design can improve these properties by selecting appropriate recognition groups as well as mitochondrial localization groups. As a common H 2 S recognition group, a dinitrophenyl (DNP) moiety has the characteristics of fast response time, high sensitivity and specific response.…”